产品展示
Anti-Phospho-CK17 (Ser44)磷酸化细胞角蛋白17抗体
点击次数：816发布时间：2012/12/26 8:37:38
更新日期：2024/9/5 14:43:40
所 在 地：其它
产品型号：BY-3239R
优质供应
详细内容
货号：BY-3239R
英文名称：Anti-Phospho-CK17 （Ser44）
中文名称：磷酸化细胞角蛋白17抗体
其他名称：39.1; CK 17; Cytokeratin17; K17; Keratin 17 antibody Keratin type I cytoskeletal 17; Keratin17; KRT 17; KRT17; KRT17 protein; PC; PC2; PCHC1.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 48kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, rat, mo
产品介绍：May play a role in the formation ａnd maintenance of various skin appendages, specifically in determining shape ａnd orientation of hair. Required for the correct growth of hair follicles, in particular for the persistence of the anagen （growth） state. Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis ａnd epithelial cell growth through binding to the adapter protein SFN ａnd by stimulating Akt/mTOR pathway. Involved in tissue repair. May be a marker of basal cell differentiation in complex epithelia ａnd therefore indicative of a certain type of epithelial ＇stem cells＇. May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells ａnd hence causing their proliferation （By similarity）. [SUBUNIT] Heterodimer of a type I ａnd a type II keratin. KRT17 associates with KRT6 isomers. Interacts with TRADD ａnd SFN. Belongs to the intermediate filament family.结构蛋白（Structural Proteins）常用于肿瘤细胞的分化、增殖及转移方面的研究。
