本公司经销CD8 alpha，CD8抗体，克隆类型为polyclonal，宿主来源是Rabbit，CD8 alphaCD8抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-4791R
英文名称：Anti-CD8 alpha
中文名称：CD8抗体
其他名称：CD 8a; CD8 alpha chain; CD8; CD8 antigen alpha chain; CD8 antigen alpha polypeptide; CD8 antigen alpha polypeptide （p32）; CD8a; CD8a antigen; CD8a molecule; CD8A_HUMAN; Leu 2; Leu2; Leu2 T lymphocyte antigen; MAL; OKT8 T cell antigen; OTTHUMP00000160760; OTTHUMP00000160764; OTTHUMP00000203528; OTTHUMP00000203721; p32; T cell antigen Leu2; T cell co receptor; T cell coreceptor; T cell surface glycoprotein CD8 alpha chain; T lymphocyte differentiation antigen T8/Leu 2; T lymphocyte differentiation antigen T8/Leu2; T-cell surface glycoprotein CD8 alpha chain; T-lymphocyte differentiation antigen T8/Leu-2; T8 T cell antigen.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 27kDa
纯化方法：affinity purified by Protein A
交叉反应：rat
产品介绍：The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha ａnd one beta chain. Both alpha ａnd beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].Function : Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains.Subunit : In general heterodimer of an alpha ａnd a beta chain linked by two disulfide bonds. Can also form homodimers. Shown to be expressed as heterodimer on thymocytes ａnd as homodimer on peripheral blood T-lymphocytes. Interacts with the MHC class I HLA-A/B2M dimer. Interacts with LCK in a zinc-dependent manner.Subcellular Location : Membrane; Single-pass type I membrane protein.Similarity : Contains 1 Ig-like V-type （immunoglobulin-like） domain.