产品展示
Anti-CXCL14CXC趋化因子14抗体
点击次数：226发布时间：2012/12/26 8:49:47
更新日期：2024/9/5 14:43:40
所 在 地：其它
产品型号：BY-1503R
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详细内容
货号：BY-1503R
英文名称：Anti-CXCL14
中文名称：CXC趋化因子14抗体
其他名称：C-X-C motif chemokine 14；Chemokine BRAK；MIP-2G；Small-inducible cytokine B14；
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 8.5/12kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, rat, mo
产品介绍：This gene belongs to the cytokine gene family which encode secreted proteins involved in immunoregulatory ａnd inflammatory processes. The protein encoded by this gene is structurally related to the CXC （Cys-X-Cys） subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. It has been implicated that this cytokine is involved in the homeostasis of monocyte-derived macrophages rather than in inflammation. [provided by RefSeq]. [FUNCTION] Potent chemoattractant for neutrophils, ａnd weaker for dendritic cells. Not chemotactic for T-cells, B-cells, monocytes, natural killer cells or granulocytes. Does not inhibit proliferation of myeloid progenitors in colony formation assays.Subcellular Location : Secreted.Tissue Specificity : Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney ａnd pancreas. Highly expressed in normal tissue without inflammatory stimuli ａnd infrequently expressed in cancer cell lines. Weakly expressed in monocyte-derived dendritic cells. Not detected in lung or unstimulated peripheral blood lymphocytes.Similarity : Belongs to the intercrine alpha （chemokine CxC） family.
