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Anti-CTGF结缔组织生长因子抗体
点击次数:270发布时间:2012/12/26 9:03:43
更新日期:2024/9/5 14:43:40
所 在 地:其它
产品型号:BY-0743R
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货号:BY-0743R
英文名称:Anti-CTGF
中文名称:结缔组织生长因子抗体
其他名称:CCN 2; CCN2; Connective Tissue Growth Factor; CTGF; Hcs 24; Hcs24; Hypertrophic chondrocyte specific protein 24; Hypertrophic chondrocyte-specific gene product 24; IGFBP8; Insulin-like Growth Factor-Binding Protein 8; MGC102839; NOV 2; NOV2.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 38kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, rat, mo, cow, pig, dog, chk
产品介绍:CTGF (connective tissue growth factor) Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes (By similarity). Mediates heparin-and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells (By similarity). Enhances fibroblast growth factor-induced DNA synthesis (By similarity). [SUBUNIT] Monomer (By similarity).Subunit : Monomer.Subcellular Location : Secreted, extracellular space, extracellular matrix (By similarity). Secreted (By similarity).Tissue Specificity : Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested.Similarity : Belongs to the CCN family. Contains 1 CTCK (C-terminal cystine knot-like) domain. Contains 1 IGFBP N-terminal domain. Contains 1 TSP type-1 domain. Contains 1 VWFC domain.生长因子和激素( Growth Factor and Hormones) 结缔组织生长因子(CTGF)是调节细胞增生、分化和细胞外基质形成的重要效应分子,可调节机体有关组织、细胞生长并与纤维化发生密切相关的一种因子,因而在肌体的各类创伤修复过程中具有重要的生理学意义。产品图片