本公司经销Connexin-45，间隙连接蛋白45抗体，克隆类型为polyclonal，宿主来源是Rabbit，Connexin-45间隙连接蛋白45抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-0652R
英文名称：Anti-Connexin-45
中文名称：间隙连接蛋白45抗体
其他名称：Connexin 45; Connexin45; CX 31.9; CX 45; CX31.9; CX45; DKFZp686P0738; Gap junction alpha 7 protein; Gap junction protein alpha 7 45kDa; Gap junction protein alpha 7; Gap junction protein, gamma 1, 45kDa; GJA 7; GJA7; GJD3.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 45kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, rat, mo, dog, pig
产品介绍：This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart ａnd in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia ａnd heart malformations.Function : RelevanceOne gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. A connexon is composed of a hexamer of connexins.Subcellular Location : Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.通道蛋白（Channel Protein） Connexin45又称缝隙连接膜通道蛋白alpha7，Cx45构成细胞间的通道,小分子成份可以借此在细胞间扩散。 Connexin-45是心肌缝隙连接蛋白的主要蛋白。产品图片Tissue/cell: mouse heart tissue; 4% Paraformaldehyde-fixed ａnd paraffin-embedded; Antigen retrieval: citrate buffer （ 0.01M, pH 6.0 ）, Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer （normal goat serum,C-0005） at 37℃ for 20 min; Incubation: Anti-Connexin-45 Polyclonal Antibody, Unconjugated（bs-0652R） 1:200, overnight at 4°C, followed by conjugation to the secondary antibody（SP-0023） ａnd DAB（C-0010） staining