本公司经销Cytomegalovirus pp65，巨细胞病毒PP65/CMV低基质磷脂蛋白抗体，克隆类型为polyclonal，宿主来源是Rabbit，Cytomegalovirus pp65巨细胞病毒PP65/CMV低基质磷脂蛋白抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-0271R
英文名称：Anti-Cytomegalovirus pp65
中文名称：巨细胞病毒PP65/CMV低基质磷脂蛋白抗体
其他名称：PP65_HCMVM; 65 kDa lower matrix phosphoprotein; 65 kDa matrix phosphoprotein; 65 kDa phosphoprotein; CMV 65 kDa lower matrix phosphoprotein; CMV pp65; Cytomegalovirus 65 kDa lower matrix phosphoprotein; Cytomegalovirus pp65; HHV 5; PP65; Tegument protein pp65; Tegument protein UL83; UL83; HCMV PP65.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 65kDa
纯化方法：affinity purified by Protein A
交叉反应：HCMV PP65
产品介绍：Cytomegalovirus is a member of the herpes virus group, which includes herpes simplex virus types 1 ａnd 2, varicella zoster virus （which causes chicken pox）, ａnd Epstein Barr virus （which causes infectious mononucleosis）. These viruses share a characteristic ability to remain dormant within the body over a long period. CMV viral genes are co-ordinately expressed in groups at various times after infection. Early viral proteins are expressed in the nucleus of infected cells within 3 to 24 hours of infection prior to the commencement of viral DNA replication. This is followed by expression of the early intermediate genes, which encode enzymes required for viral DNA replication. After 48 to 72 hours, a number of late viral antigens may be demonstrated in the nuclei ａnd cytoplasm of infected cells. pp65 is a 65kD phosphorylated glycoprotein ａnd is the most abundant of the late antigens. Subunit : Interacts with host NCL/nucleolin. Interacts with host IFI16.Tissue Specificity : Virion tegument （Potential）. Host nucleus. Host cytoplasm. Note=As part of the incoming virion, pp65 is targeted to the nucleus immediately after infection. The newly synthesized pp65 is observed in the nucleus until some time after 48 hours postinfection. Thereafter, pp65 is probably exported ａnd accumulates in the cytoplasm. Also found in dense bodies.Similarity : Belongs to the herpesviridae pp65 family.细胞巨化病毒是一种疱疹病毒, 易引起先天性畸形，且患者在接受大量输血和免疫抑制力治疗时它是引起并发症的主要生物因子。巨细胞病毒是一种感染肺、肾、肠和其他器官的条件致病菌。该抗体识别分子量为52、65、72以及86kDa的立即早期非结构抗原。该抗原在感染2小时后即可被检测到。而感染96小时达到峰值，并持续整个CMV周期。 初期感染此病毒的孕妇中近一半会将此病传播给她的胎儿，被传染的胎儿长大后易智力低下，失明或耳聋。