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Anti-CCL4/MIP-1 Beta巨噬细胞炎性蛋白1β抗体
点击次数：282发布时间：2012/12/26 9:17:19
更新日期：2024/9/5 14:43:40
所 在 地：其它
产品型号：BY-2475R
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货号：BY-2475R
英文名称：Anti-CCL4/MIP-1 Beta
中文名称：巨噬细胞炎性蛋白1β抗体
其他名称： Macrophage Inflammatory Protein 1 beta; MIP-1 Beta; MIP-1β; Secreted protein G 26; ACT 2; ACT2; AT744.1; CC chemokine ligand 4; CCL4; ccl4l 1; CCL4L1; Chemokine CC Motif Ligand 4; G 26 T lymphocyte secreted protein; HC21; LAG 1; LAG1; Lymphocyte activation gene 1; Lymphocyte activation gene 1 protein; Macrophage inflammatory protein 1 beta; MGC104418; MGC126025; MGC126026; MIP1 beta; MIP1B; MIP1B1; PAT 744; Protein H400; SCYA2; SCYA4; Secreted protein G26; SIS gamma; Small inducible cytokine A4; T cell activation protein 2
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 10kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
产品介绍：MIP1 alpha ａnd MIP1 beta were originally co-purified from medium conditioned by an LPS-stimulated murine macrophage cell line. Human MIP1 beta refers to the products of several independently cloned cDNAs, including Act2, PAT 744, hH400, G26, HIMAP, HC21, ａnd MAD 5a. The predicted protein products of these cDNAs represent variants that are between 94% - 98% identical ａnd these proteins are all approximately 75% homologous to murine MIP1 beta. MIP1 beta also shares approximately 70% amino acid identity with MIP1 alpha. MIP1 proteins are expressed primarily in T cells, B cells, ａnd monocytes after antigen or mitogen stimulation. The MIP1 proteins have chemoattractant ａnd adhesive effects on lymphocytes, with MIP1 alpha ａnd MIP1 beta preferentially attracting CD8+ ａnd CD4+ T cells, respectively. A signal transducing receptor designated the CC chemokine receptor 1 （CC CKR1） with seven transmembrane domains that binds MIP1 alpha, MIP1 beta, MCP1 ａnd RANTES with varying affinities has been isolated.
