产品展示
Anti-Contactin-1神经细胞表面蛋白F3
点击次数:307发布时间:2012/12/26 9:19:04
更新日期:2024/9/5 14:43:40
所 在 地:其它
产品型号:BY-2667R
优质供应
详细内容
货号:BY-2667R
英文名称:Anti-Contactin-1
中文名称:神经细胞表面蛋白F3
其他名称:CNTN 1; CNTN; CNTN1; Contactin1; Contactin 1; Contactin-1; F3; F3cam; Glycoprotein gp135v gp 135; gp135; Neural cell surface protein F3.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 135kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat, cow, dog, hrs, pig, Rb
产品介绍:Contactin 6 is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein which functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system.Subunit : Monomer. Interacts with CNTNAP1 in cis form. Binds to the carbonic-anhydrase like domain of protein-tyrosine phosphatase zeta. Interacts with NOTCH1 and TNR.Subcellular Location : Isoform 1: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side. Isoform 2: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side.Tissue Specificity : Strongly expressed in brain and in neuroblastoma and retinoblastoma cell lines. Lower levels of expression in lung, pancreas, kidney and skeletal muscle.Similarity : Belongs to the immunoglobulin superfamily. Contactin family.Contains 4 fibronectin type-III domains.Contains 6 Ig-like C2-type (immunoglobulin-like) domains.