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Anti-MRC1/CD206巨噬细胞甘露糖受体抗体
点击次数：309发布时间：2012/12/26 9:20:06
更新日期：2024/9/5 14:43:40
所 在 地：其它
产品型号：BY-2664R
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货号：BY-2664R
英文名称：Anti-MRC1/CD206
中文名称：巨噬细胞甘露糖受体抗体
其他名称：Mannose Receptor; Macrophage mannose receptor 1; C-type lectin domain family 13 member D; CD 206; CD206; CD206 antigen; CLEC13D; Macrophage mannose receptor 1; Macrophage mannose receptor; Mannose receptor C type 1; MMR; MRC 1; MRC-1; OTTHUMP00000045206.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 160kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, Rb, shp, pig, hrs, dog
产品介绍：The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, ａnd neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, ａnd fungi so that they can be neutralized by phagocytic engulfment. This gene is in close proximity to MRC1L1. The gene loci including this gene, MRC1L1, as well as LOC340843 ａnd LOC340893, consist of two nearly identical, tandemly linked genomic regions, which are thought to be a part of a duplicated region. [provided by RefSeq].Subcellular Location : Endosome membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein.Tissue Specificity : Detected in macrophages.Similarity : Contains 8 C-type lectin domains. Contains 1 fibronectin type-II domain.Contains 1 ricin B-type lectin domain.巨噬细胞甘露糖受体,主要存在于巨噬细胞膜表面的模式识别受体，能够特异性识别甘露糖、岩藻糖或N-乙酰葡糖胺，介导巨噬细胞吞噬抗原，启动免疫反应.
