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货号：BY-2672R
英文名称：Anti-Cathepsin C
中文名称：组织蛋白酶C抗体
其他名称：Dipeptidyl peptidase I; AI047818; CATC; Cathepsin C; Cathepsin J; CPPI; CTSC; Dipeptidyl peptidase 1; Dipeptidyl transferase; DPP I; DPPI; EC 3.4.14.1; HMS; JP; JPD; MGC126959; PALS; PLS.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 52kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, pig, dog, Rb, hrs, cow, chk
产品介绍：The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy ａnd light chains, both produced from a single protein precursor, ａnd a residual portion of the propeptide acts as an intramolecular chaperone for the folding ａnd stabilization of the mature enzyme. This enzyme requires chloride ions for activity ａnd can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis ａnd periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
