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Anti-CACNA1G/Cav3.1电压依赖性钙通道Cav3.1抗体
点击次数:256发布时间:2012/12/26 9:31:19
更新日期:2024/9/5 14:43:40
所 在 地:其它
产品型号:BY-2781R
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货号:BY-2781R
英文名称:Anti-CACNA1G/Cav3.1
中文名称:电压依赖性钙通道Cav3.1抗体
其他名称:calcium channel voltage dependent alpha 1G subunit; calcium channel voltage dependent T type alpha 1G subunit; calcium channel voltage dependent T type alpha1G subunit; CaV T1; Cav3 1; cav3 1c; NBR13; voltage dependent calcium channel alpha 1G subunit isoform 11; voltage dependent T type calcium channel subunit alpha 1G.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 262kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat, cow, dog, Gpig
产品介绍:Voltage activated calcium channels can be distinguished based on their voltage dependence, deactivation, and single channel conductance. Low voltage activated calcium channels are referred to as 'T' type because their currents are both transient, owing to fast inactivation, and tiny, owing to small conductance. T type channels are thought to be involved in pacemaker activity, low threshold calcium spikes, neuronal oscillations and resonance, and rebound burst firing.Subcellular Location : Membrane; Multi-pass membrane protein.Tissue Specificity : Highly expressed in brain, in particular in the amygdala, subthalamic nuclei, cerebellum and thalamus. Moderate expression in heart; low expression in placenta, kidney and lung. Also expressed in colon and bone marrow and in tumoral cells to a lesser extent. Highly expressed in fetal brain, but also in peripheral fetal tissues as heart, kidney and lung, suggesting a developmentally regulated expression.Similarity : Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. CACNA1G subfamily.