产品展示
Anti-CCKAR胆囊收缩素A受体抗体
点击次数：210发布时间：2012/12/26 9:49:57
更新日期：2024/9/5 14:43:40
所 在 地：其它
产品型号：BY-11514R
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货号：BY-11514R
英文名称：Anti-CCKAR
中文名称：胆囊收缩素A受体抗体
其他名称：CCK A;CCK A receptor;CCK AR;CCK-AR.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 34kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
产品介绍：The cholecystokinin （CCK） family of peptide hormones have been implicated in numerous important physiologic events. These appear to be mediated through 2 general classes of receptors, A （CCKAR）and B （CCKBR）, based on their binding affinities for CCK/gastrin family peptides. Through binding to class A receptors, CCK is a major physiologic mediator of gallbladder contraction ａnd pancreatic enzyme secretion. It appears to play a role in slowing gastric emptying, relaxation of the sphincter of Oddi, ａnd potentiation of insulin secretion. Further, it has been implicated as a mediator of pancreatic growth ａnd tumorigenesis. Class A receptors have also been described in the anterior pituitary, myenteric plexus, ａnd regions of the central nervous system, where they have been implicated in the pathogenesis of feeding disorders, Parkinson disease, schizophrenia, ａnd drug addiction. Subcellular Location : Integral membrane protein
