本公司经销Calcipressin 3，钙调神经磷酸酶调节蛋白3抗体（唐氏综合征候选区域蛋白1样蛋白3），克隆类型为polyclonal，宿主来源是Rabbit，Calcipressin 3钙调神经磷酸酶调节蛋白3抗体（唐氏综合征候选区域蛋白1样蛋白3）可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-11542R
英文名称：Anti-Calcipressin 3
中文名称：钙调神经磷酸酶调节蛋白3抗体（唐氏综合征候选区域蛋白1样蛋白3）
其他名称：Calcipressin-3;Down syndrome candidate region 1 like 2; regulator of calcineurin 3;Down syndrome candidate region 1 like protein 2;Down syndrome candidate region 1-like protein 2;Down syndrome critical region gene 1 like 2;DSCR1L2;hRCN3;MCIP3;Myocyte enriched calcineurin interacting protein 3;Myocyte-enriched calcineurin-interacting protein 3;RCAN family member 3;RCAN3;RCAN3_HUMAN;RCN3;Regulator of calcineurin 3.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 27kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
产品介绍：Calcineurin is a Ca（2+） dependent protein phosphatase that is involed in several neuornal functions. Proteins belonging to the RCAN （Regulator of calcineurin） family modulate the activity of Calcineurin through a valine-rich region within their carboxyl tail. RCANs compete with NFATs （Nuclear factor of activated T-cells） for binding to the same docking site in calcineurin, which results in either inhibition or activation of calcineurin activity. Calcipressin-2, also known as RCAN2 ａnd DSCR1L1 （Down syndrome candidate region 1-like 1）, is a 197 amino acid protein that is highly expressed in both the cytoplasm ａnd nucleus of neurons ａnd is the only RCAN family member that is found in glial cells. Calcipressin-3, also known as RCAN3 ａnd DSCR1L2 （Down syndrome candidate region 1-like protein 2）, is a 241 amino acid protein that potentially is involved in central nervous system development. Calcipressin-3 interacts with cardiac troponin I, suggesting that it may play a role in cardiac contraction events.Function : Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.Tissue Specificity : Highest expression in heart, skeletal muscle kidney, liver ａnd peripheral blood leukocytes. Lower expression in all other tissues.Similarity : Belongs to the RCAN family.