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Anti-p22-phox/Cytochrome b245 Light Chain细胞色素b245轻链抗体
点击次数：394发布时间：2012/12/26 10:08:35
更新日期：2024/9/5 14:43:40
所 在 地：其它
产品型号：BY-3879R
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货号：BY-3879R
英文名称：Anti-p22-phox/Cytochrome b245 Light Chain
中文名称：细胞色素b245轻链抗体
其他名称：Superoxide-generating NADPH oxidase light chain subunit; CYBA; Cytochrome b（558） alpha chain; Cytochrome b558 subunit alpha; Neutrophil cytochrome b 22 kDa polypeptide; p22 phagocyte B-cytochrome; p22 phox; p22phox.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 22kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
产品介绍：Mox1 ａnd the glycoprotein gp91-phox are largely related proteins that are essential components of the NADPH oxidase. The superoxide-generating NADPH oxidase is present in phagocytes, neuroepithelial bodies, vascular smooth muscle cells ａnd endothelial cells. It includes a membrane-bound flavocytochrome containing two subunits, gp91-phox ａnd p22-phox, ａnd the cytosolic proteins p47-phox ａnd p67-phox. During activation of the NADPH oxidase, p47-phox ａnd p67-phox migrate to the plasma membrane, where they associate with the flavocytochrome cytochrome b558 to form the active enzyme complex. The p22- ａnd gp91-phox subunits also function as surface O2 sensors that initiate cellular signaling in response to hypoxic conditions.Function : Cytochrome b245 Light Chain/p22phox is a critical component of the membrane-bound oxidase complex that generates superoxide. It complexes with NOX3 to form a functional NADPH oxidase.Subcellular Location : Cell Membranep22phox又称中性粒细胞色素b22kDa的多肽，主要用于心血管病及心肺功能的研究。
