产品展示
Anti-CDK8周期素依赖性激酶8抗体
点击次数：282发布时间：2012/12/26 10:14:15
更新日期：2024/9/5 14:43:40
所 在 地：其它
产品型号：BY-0570R
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详细内容
货号：BY-0570R
英文名称：Anti-CDK8
中文名称：周期素依赖性激酶8抗体
其他名称：Cyclin Dependent Kinase 8; Cell Division Kinase 8; Cell division protein kinase 8; K35; Mediator complex subunit CDK8; Mediator of RNA polymerase II transcription subunit CDK8; Protein kinase K35.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 53kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, rat, mo
产品介绍：A family of proteins designated as cdks are critical regulators of cell cycle progression. The prototype member of this family, p34 / Cdc2, ａnd a related protein Cdk2, function late in the cycle while Cdk4 ａnd Cdk6 are critically involved in G1 to S progression. p54 / Cdk8 interacts exclusively with CyclinC. The Cdk8-CyclinC complex activates the kinase. Because of analogy with yeast Cdk8, it has been proposed that the human Cdk8-CyclinC may interact with RNA polymerase, thus influencing the transcription mechanism（s） that lead to cell division. Also known as: Cyclin Dependent Kinase 8; Cell Division Kinase 8; Cell division protein kinase 8; K35; Mediator complex subunit CDK8; Mediator of RNA polymerase II transcription subunit CDK8; Protein kinase K35.
