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Anti-CGRP/CGRP2CGRP降钙素基因相关肽抗体
点击次数:257发布时间:2012/12/26 10:17:52
更新日期:2024/9/5 14:43:40
所 在 地:其它
产品型号:BY-0791R
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详细内容
本公司经销CGRP/CGRP2,CGRP降钙素基因相关肽抗体,克隆类型为polyclonal,宿主来源是Rabbit,CGRP/CGRP2CGRP降钙素基因相关肽抗体可应用于WB、elisa、IP、IF、IHC等实验,欢迎垂询订购!
货号:BY-0791R
英文名称:Anti-CGRP/CGRP2
中文名称:CGRP降钙素基因相关肽抗体
其他名称:Procalcitonin; Alpha type CGRP; Alpha type CGRP; Beta type CGRP; CALC 1; CALC A; CALC1; CALC2; CALCA; CALCB; Calcitonin 1; Calcitonin 2; Calcitonin gene related peptide 1; Calcitonin gene related peptide 1 precursor; Calcitonin gene related peptide; Calcitonin gene related peptide I; Calcitonin gene related peptide II; Calcitonin related polypeptide alpha; Calcitonin related polypeptide beta; CGRP; CGRP I; CGRP II; CGRP1; CGRP2; CT; Calcitonin/calcitonin related polypeptide alpha; Katacalcin; MGC126648.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 5/14kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, rat, mo, pig, cow, chk
产品介绍:CGRP is present in C-cells of the thyroid and in central and peripheral nerves. CGRP has several important physiologic roles: it is a potent vasodilator, and can affect the force and rate of heart beat; it can modulate acetylcholine receptor function at the neuromuscular junction; it has been demonstrated to block tolerance to morphine; and it can modulate antigen presentation in Langerhans cells in the skin. Despite these important physiologic functions, therapeutic strategies using CGRP have been impeded due to the lack of a cloned CGRP receptor with which ligands could be developed.Subcellular Location : Secreted CGRP活性多肽,有37个氨基酸组成,具有多种生理功能,其药理作用已受到广泛重视. CGRP (又称CGRP-1/2或CGRPa/β)广泛分布于神经系统的一种神经肽,在外周及脊髓参与伤害性信息的传递及痛敏化的形成,并与P物质、兴奋性氨基酸、辣椒素1型受体、趋化因子、激活素、麻素受体、阿片受体、神经生长因子、血管活性肠肽、5-羟色胺、糖皮质激素等生物活性物质或受体在痛觉调制过程中存在相互影响。产品图片Tissue/cell: human endometrium carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-CGRP/CGRP2 Polyclonal Antibody, Unconjugated(bs-0791R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining