本公司经销CACNA1A/Cav2.1，电压依赖性钙通道Cav2.1抗体，克隆类型为polyclonal，宿主来源是Rabbit，CACNA1A/Cav2.1电压依赖性钙通道Cav2.1抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-3930R
英文名称：Anti-CACNA1A/Cav2.1
中文名称：电压依赖性钙通道Cav2.1抗体
其他名称：APCA; BI; Brain calcium channel 1; Brain calcium channel I; Cach4; Cacn3; Cacna1a; Cacnl1a4; Calcium channel alpha 1A subunit; Calcium channel L type alpha 1 polypeptide; Calcium channel L type alpha-1 polypeptide isoform 4; Calcium channel voltage dependent, P/Q type alpha 1A subunit; CAV2.1; EA2; FHM; HPCA; MHP; MHP1; RAT brain class A; RBA-I; SCA6; Voltage-dependent P/Q-type calcium channel alpha-1A subunit; Voltage-gated calcium channel alpha subunit Cav2.1.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 276kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, pig, cow, Rb
产品介绍：Cav2.1 is a voltage-sensitive calcium channels （VSCC） which belongs to the calcium channel alpha-1 subunit family. Cav2.1 mediates the entry of calcium ions into excitable cells ａnd is also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division ａnd cell death. Cav2.1 （isoform alpha-1A） gives rise to P and/or Q-type calcium currents. Voltage-dependent calcium channels are multisubunit complexes, consisting of alpha-1, alpha-2, beta ａnd delta subunits in a 1:1:1:1 ratio. The channel activity is directed by the pore-forming ａnd voltage-sensitive alpha-1 subunit. In many cases, this subunit is sufficient to generate voltage-sensitive calcium channel activity. The auxiliary subunits beta ａnd alpha-2/delta linked by a disulfide bridge regulate the channel activity.Subcellular Location : Membrane; Multi-pass membrane protein.Tissue Specificity : Brain specific; mainly found in cerebellum, cerebral cortex, thalamus ａnd hypothalamus. Expressed in the small cell lung carcinoma cell line SCC-9. No expression in heart, kidney, liver or muscle. Purkinje cells contain predominantly P-type VSCC, the Q-type being a prominent calcium current in cerebellar granule cells.Similarity : Belongs to the calcium channel alpha-1 subunit （TC 1.A.1.11） family. CACNA1A subfamily.