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Anti-CACH6/Cav2.3L型钙通道蛋白a1亚型6抗体
点击次数:419发布时间:2012/12/26 10:21:22
更新日期:2024/9/5 14:43:40
所 在 地:其它
产品型号:BY-3933R
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详细内容
货号:BY-3933R
英文名称:Anti-CACH6/Cav2.3
中文名称:L型钙通道蛋白a1亚型6抗体
其他名称:BII; Brain calcium channel II; CAC 1E; CAC1E; CACH 6; CACH6; CACNA1E; Cacnl1 a6; CACNL1A6; Calcium channel, L type, alpha 1 polypeptide, isoform 6; calcium channel, R type; Cav 2.3; Cchra 1; Cchra1; Voltage dependent R type calcium channel subunit alpha 1E; Voltage gated calcium channel subunit alpha Cav2.3.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 262kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat, Rb, Gpig, hrs, cow, dog
产品介绍:Calcium channels mediate the influx of calcium ions into the cell following membrane polarisation. R-type calcium channels such as Cav2.3 belong to the "high voltage-activated" group and are blocked by nickel. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Each of these proteins exists as multiple isoforms, either encoded by different genes or arising from alternative splicing of transcripts. Cav2.3 is an alpha-1 subunit and has 24 transmembrane segments, which form the pore through which ions pass into the cell. Calcium channels containing the Cav2.3 subunit may be involved in the modulation of firing patterns of neurons, which is important for information processing. Subcellular Location : Membrane; Multi-pass membrane protein.Tissue Specificity : Expressed in neuronal tissues and in kidney.Similarity : Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. CACNA1E subfamily.Contains 1 EF-hand domain.