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Anti-Phospho-cdc25A (Ser177)磷酸化细胞分裂周期蛋白25抗体
点击次数：474发布时间：2012/12/26 10:24:01
更新日期：2024/9/5 14:43:40
所 在 地：其它
产品型号：BY-5261R
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详细内容
货号：BY-5261R
英文名称：Anti-Phospho-cdc25A （Ser177）
中文名称：磷酸化细胞分裂周期蛋白25抗体
其他名称：Cdc 25a; CDC25A2; Cell division cycle 25 homolog A （S. pombe）; Cell division cycle 25A; Cell division cycle 25A isoform a; Cell division cycle 25A isoform bv D9Ertd393ev Dual specificity phosphatase CDC25A; EC 3.1.3.48; M phase inducer phosphatase 1; MGC115549.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 59kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, rat, mo
产品介绍：Cyclin dependent kinases are positively regulated by association with cyclins ａnd negatively regulated by binding to inhibitory subunits. The activity of cyclin dependent kinases is also regulated by the phosphorylation status, which is controlled by the antagonistic action of Wee1 kinase ａnd CDC25 phosphatases. Three CDC25 genes are present in human cells: CDC25A, CDC25B, ａnd CDC25C. These three genes function at different phases of the cell cycle. Whereas CDC25A ａnd CDC25B are expressed throughout the cell cycle, with peak expression in G1 for CDC25A ａnd in both G1 S phase ａnd G2 for CDC25B, CDC25C is predominantly expressed in G2.CDC25家族的组成哺乳动物中CDC25家族一共包括3种同源异构体（CDC25A、CDC25B、CDC25C），约有50%的序列同源，是一组在细胞周期调控中发挥巨大作用的苏/酪氨酸双功能酶 。不同的CDC25家族蛋白在细胞周期中的作用时相亦有差异，CDC25A和CDC25C分别在S期和M期发挥主要作用。
