本公司经销phospho-C-Myc（Thr358），磷酸化致癌基因C-Myc抗体，克隆类型为polyclonal，宿主来源是Rabbit，phospho-C-Myc（Thr358）磷酸化致癌基因C-Myc抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！

货号：BY-4017R
英文名称：Anti-phospho-C-Myc（Thr358）
中文名称：磷酸化致癌基因C-Myc抗体
其他名称：Myc（Phospho-Thr358）; AU016757; Avian myelocytomatosis viral oncogene homolog; bHLHe39; c Myc; Cellular myelocytomatosis oncogene; MGC105490; MRTL; Myc protein; Myc proto oncogene protein; Myc-related translation/localization regulatory factor; Myc2; myca; Myelocytomatosis oncogene a; Myelocytomatosis oncogene; Niard; Nird; Oncogene Myc; Protooncogene homologous to myelocytomatosis virus; RNCMYC; Transcription factor p64; Transcriptional regulator Myc-A; v myc avian myelocytomatosis viral oncogene homolog; v myc myelocytomatosis viral oncogene homolog （avian）; V-Myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog （avian）; zc-myc.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 49kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, hrs
产品介绍：The c-Myc protein is a transcription factor, which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells ａnd plays an important role in cellular proliferation, differentiation, apoptosis ａnd cell cycle progression. The phosphorylation of c-Myc has been investigated ａnd previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 ａnd C-Jun N terminal Kinase （JNK） in cell proliferation ａnd cell cycle regulation. Studies also have shown that c-Myc is essential for tumor cell development in vasculogenesis ａnd angiogenesis that distribute blood throughout the cells, ａnd which brought extensive attention in the development of new therapeutic approach for cancer treatment.Function : Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5＇-CAC[GA]TG-3＇. Seems to activate the transcription of growth-related genes.Subcellular Location : Nucleus