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肿瘤坏死因子受体超家族成员9抗体,Anti-CD137/TNFRSF9抗体
点击次数:313发布时间:2012/12/3 14:05:19
更新日期:2022/5/31 10:00:27
所 在 地:欧洲
产品型号:
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详细内容
【产品名称】:肿瘤坏死因子受体超家族成员9抗体,Anti-CD137/TNFRSF9抗体
【产品类型】:一抗
【产品编号】:BYk-2449R
【相关标记】: HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647
【性 状】: Lyophilized or Liquid
【浓 度】: 1mg/1ml
【亚 型】: IgG
【规 格】:0.1ml/100ug,0.2ml/200ug
【抗体来源】: Rabbit OR MOUSE
【克隆类型】: polyclonal or monoclonal
【产品用途】:科研实验,用于免疫组化实验,WB实验、IF、IP、ELISA实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
【贮 存】: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
【产品介绍】: CD137 exists on the cell surface as a monomer with a molecular mass of 30 kDa and as a dimer of 55 kDa. Human and mouse CD137 share 60% amino acid identity. CD137 (4-1BB), a member of the tumour necrosis factor receptor superfamily, is a type I transmembrane glycoprotein expressed on the cell surface of activated splenic T cells and thymocytes. The functions of CD137 in T lymphocytes include regulating activation, proliferation and apoptosis. CD137 and CD28 are costimulatory molecules of T cell activation. Costimulatory molecules are important in initiating anti-tumor immune responses. CD137 plays an important role in regulating T-cell-dependent immune responses. Expression of CD137 correlates negatively with lymphocyte proliferation and positively with the degree of activation-induced cell death caused by mitogen overstimulation. In monocytes, CD137 induces activation, promotes adherence and prolongs survival.
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“肿瘤坏死因子受体超家族成员9抗体,Anti-CD137/TNFRSF9抗体”应用于IHC、WB、 IF、IP、ELISA,质量保证,无效免费退换,另外本公司生产经营ELISA试剂盒,生物试剂,细胞株,培养基,各种标记二抗、免疫印迹常用试剂、免疫组化常用试剂,欢迎来电咨询!