产品展示
细胞表面趋化因子受体2抗体,Anti-CXCR2/CD182抗体
点击次数：213发布时间：2012/12/17 13:48:28
更新日期：2022/5/31 10:00:52
所 在 地：中国大陆
产品型号：
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产品名称 细胞表面趋化因子受体2抗体,Anti-CXCR2/CD182抗体
产品编号 BYk-1629R
相关标记 HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-Cy5 PE-Cy5.5
PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647
浓 度 1mg/1ml
抗体来源 Rabbit OR MOUSE
克隆类型 polyclonal or monoclonal
产品类型 一抗
产品用途 科研实验，用于免疫组化实验，WB实验、IF、IP、ELISA实验，相应的标记抗体有HRP标记抗体，FITC标记，BIO等。
性 状 Lyophilized or Liquid
亚 型 IgG
细胞表面趋化因子受体2抗体,Anti-CXCR2/CD182抗体保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
细胞表面趋化因子受体2抗体,Anti-CXCR2/CD182抗体产品说明：
The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 （IL8）. It binds to IL8 with high affinity, ａnd transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine （C-X-C motif） ligand 1 （CXCL1/MGSA）, a protein with melanoma growth stimulating activity, ａnd has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Alternatively spliced variants, encoding the same protein, have been identified.
