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转录因子E2F-1抗体,Anti-E2F1抗体
点击次数：191发布时间：2012/12/17 17:52:55
更新日期：2022/5/31 10:00:52
所 在 地：中国大陆
产品型号：
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产品名称 转录因子E2F-1抗体,Anti-E2F1抗体
产品编号 BYk-0599R
相关标记 HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-Cy5 PE-Cy5.5
PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647
浓 度 1mg/1ml
抗体来源 Rabbit OR MOUSE
克隆类型 polyclonal or monoclonal
产品类型 一抗
产品用途 科研实验，用于免疫组化实验，WB实验、IF、IP、ELISA实验，相应的标记抗体有HRP标记抗体，FITC标记，BIO等。
性 状 Lyophilized or Liquid
亚 型 IgG
转录因子E2F-1抗体,Anti-E2F1抗体保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
转录因子E2F-1抗体,Anti-E2F1抗体产品说明：
E2F＇s are DNA binding proteins, which associate with negative regulators, such as the retinoblastoma p107 protein, resulting in an altered rate of gene transcription. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins （DP）, a transactivation domain enriched in acidic amino acids, ａnd a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein ａnd another 2 members, E2F2 ａnd E2F3, have an additional cyclin binding domain. E2F1 is proposed to be involved in several cellular processes that range from tumor suppressor, cell progression ａnd oncogenesis. E2F1 overexpression can also drive cells into apoptosis.
