产品展示
转录因子E2F-5抗体,Anti-E2F5抗体
点击次数：192发布时间：2012/12/18 8:56:38
更新日期：2022/5/31 10:00:52
所 在 地：中国大陆
产品型号：
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产品名称 转录因子E2F-5抗体,Anti-E2F5抗体
产品编号 BYk-1734R
相关标记 HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-Cy5 PE-Cy5.5
PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647
浓 度 1mg/1ml
抗体来源 Rabbit OR MOUSE
克隆类型 polyclonal or monoclonal
产品类型 一抗
产品用途 科研实验，用于免疫组化实验，WB实验、IF、IP、ELISA实验，相应的标记抗体有HRP标记抗体，FITC标记，BIO等。
性 状 Lyophilized or Liquid
亚 型 IgG
转录因子E2F-5抗体,Anti-E2F5抗体保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
转录因子E2F-5抗体,Anti-E2F5抗体产品说明：
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle ａnd action of tumor suppressor proteins ａnd is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins （DP）, a transactivation domain enriched in acidic amino acids, ａnd a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated ａnd is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein ａnd E2F4 interact with tumor suppressor proteins p130 ａnd p107, but not with pRB. Alternative splicing results in multiple variants encoding different isoforms.
