产品展示
细胞转录因子ELK1抗体,Anti-ELK1抗体
点击次数：196发布时间：2012/12/18 9:40:43
更新日期：2022/5/31 10:00:52
所 在 地：中国大陆
产品型号：
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产品名称 细胞转录因子ELK1抗体,Anti-ELK1抗体
产品编号 BYk-1398R
相关标记 HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-Cy5 PE-Cy5.5
PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647
浓 度 1mg/1ml
抗体来源 Rabbit OR MOUSE
克隆类型 polyclonal or monoclonal
产品类型 一抗
产品用途 科研实验，用于免疫组化实验，WB实验、IF、IP、ELISA实验，相应的标记抗体有HRP标记抗体，FITC标记，BIO等。
性 状 Lyophilized or Liquid
亚 型 IgG
细胞转录因子ELK1抗体,Anti-ELK1抗体保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
细胞转录因子ELK1抗体,Anti-ELK1抗体产品说明：
The transcription factor Elk1 is a component of the ternary complex that binds the serum response element （SRE） ａnd mediates gene activity in response to serum ａnd growth factors. Elk1 is phosphorylated by MAP kinase pathways at a cluster of S/T motifs at its C terminus. Phosphorylation at these sites, particularly Ser383, is critical for transcriptional activation by Elk1. Elk1 appears to be a direct target of activated MAP kinase. Biochemical studies indicate that Elk1 is a good substrate for MAP kinase, the kinetics of Elk1 phosphorylation ａnd activation correlate with MAP kinase activity, ａnd interfering mutants of MAP kinase block Elk1 activation in vivo. More recent studies have shown that Elk1 （Ser383） is also a target of the Stress Activated Kinase SAPK/JNK. Phosphorylation of Elk1 has also been implicated in synaptic plasticity in the adult hippocampus.
