产品展示
红细胞生成素受体抗体,Anti-EPOR抗体
点击次数：218发布时间：2012/12/18 10:22:41
更新日期：2022/5/31 10:00:52
所 在 地：中国大陆
产品型号：
优质供应
详细内容
博研生物抗体售前、售中、售后免费技术服务，欢迎致电索说明书
客服电话：021 60340850 021 60340830 021
客服QQ ：827774711 349199432 372584443
产品名称 红细胞生成素受体抗体,Anti-EPOR抗体
产品编号 BYk-1424R
相关标记 HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-Cy5 PE-Cy5.5
PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647
浓 度 1mg/1ml
抗体来源 Rabbit OR MOUSE
克隆类型 polyclonal or monoclonal
产品类型 一抗
产品用途 科研实验，用于免疫组化实验，WB实验、IF、IP、ELISA实验，相应的标记抗体有HRP标记抗体，FITC标记，BIO等。
性 状 Lyophilized or Liquid
亚 型 IgG
红细胞生成素受体抗体,Anti-EPOR抗体保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
红细胞生成素受体抗体,Anti-EPOR抗体产品说明：
The erythropoietin receptor （EPOR） is a member of the cytokine receptor family. There are several isoforms including: EPOR-F （full length）, EPOR-S （soluble form）, ａnd EPOR-T （truncated form）. Upon erythropoietin （EPO） binding, the EPOR activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase ａnd STAT transcription factors. The stimulated EPOR appears to have a role in erythroid cell survival. Defects in the EPOR may produce erythroleukemia ａnd familial erythrocytosis. A functional EPOR is found in the cardiovascular system, including endothelial cells ａnd cardiomyocytes, ａnd data suggest that the EPO/EPO receptor system plays an important role in cardiac function. In animal studies, treatment with EPO during ischemia/reperfusion in the heart has been shown to limit the infarct size ａnd the extent of apoptosis.
