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DNA切除修复蛋白1抗体,Anti-ERCC1抗体
点击次数：263发布时间：2012/12/18 10:28:33
更新日期：2022/5/31 10:00:52
所 在 地：中国大陆
产品型号：
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产品名称 DNA切除修复蛋白1抗体,Anti-ERCC1抗体
产品编号 BYk-1726R
相关标记 HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-Cy5 PE-Cy5.5
PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647
浓 度 1mg/1ml
抗体来源 Rabbit OR MOUSE
克隆类型 polyclonal or monoclonal
产品类型 一抗
产品用途 科研实验，用于免疫组化实验，WB实验、IF、IP、ELISA实验，相应的标记抗体有HRP标记抗体，FITC标记，BIO等。
性 状 Lyophilized or Liquid
亚 型 IgG
DNA切除修复蛋白1抗体,Anti-ERCC1抗体保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
DNA切除修复蛋白1抗体,Anti-ERCC1抗体产品说明：
The product of this gene functions in the nucleotide excision repair pathway, ａnd is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease （also known as ERCC4）, ａnd the heterodimeric endonuclease catalyzes the 5＇ incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair ａnd in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, ａnd polymorphisms that alter expression of this gene may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand.
