产品展示
雌激素受体α抗体,Anti-ER-Alpha抗体
点击次数：181发布时间：2012/12/18 11:07:47
更新日期：2022/5/31 10:00:52
所 在 地：中国大陆
产品型号：
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产品名称 雌激素受体α抗体,Anti-ER-Alpha抗体
产品编号 BYk-0254R
相关标记 HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-Cy5 PE-Cy5.5
PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647
浓 度 1mg/1ml
抗体来源 Rabbit OR MOUSE
克隆类型 polyclonal or monoclonal
产品类型 一抗
产品用途 科研实验，用于免疫组化实验，WB实验、IF、IP、ELISA实验，相应的标记抗体有HRP标记抗体，FITC标记，BIO等。
性 状 Lyophilized or Liquid
亚 型 IgG
雌激素受体α抗体,Anti-ER-Alpha抗体保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
雌激素受体α抗体,Anti-ER-Alpha抗体产品说明：
Estrogen ａnd progesterone receptor are members of a family of transcription factors that are regulated by the binding of their cognate ligands. The interaction of hormone-bound estrogen receptors with estrogen responsive elements（EREs） alters transcription of ERE-containing genes. The carboxy terminal region of the estrgen receptor contains the ligand binding domain, the amino terminus serves as the transactivation domain, ａnd the DNA binding domain is centrally located. Two forms of estrogen receptor have been identified, ER Alpha ａnd ER Beta. ER Alpha ａnd ER Beta have been shown to be differentially activated by various ligands. The biological response to progesterone is mediated by two distinct forms of the human progesterone receptor （hPR-A ａnd hPR-B）, which arise from alternative splicing. In most cells, hPR-B functions as a transcriptional activator of progesterone-responsive gene, whereas hPR-A function as a transcriptional inhibitor of all steroid hormone receptors.
