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马间充质干细胞

点击次数:435发布时间:2013/4/25 19:06:20

马间充质干细胞

更新日期:2024/8/15 17:15:41

所 在 地:美洲

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简单介绍:马间充质干细胞马间充质干细胞(DMSC-ad) 提取于马脂肪组织,代冻存。 间充质干细胞在成人的干细胞中数量恒定。它们有发育为成熟细胞的潜在能力,从而产生脂肪、软骨、骨骼和肌肉。这些特性以及它们发育中的可塑性,使人们对用间充质干细胞来替换受损组织的潜在可能性产生了极大的兴趣。间充质干细胞培养在含有转化生长因子,无血清的培养基中将分化成软骨细胞,培养在含血清,维生素C和地塞米松的培养基中将分化成造骨细胞。间充质干细胞有更新和分化成不同间充质组织系的能力。间充质干细胞可以通过培养来增加数量,然后移植到受损部位或植入生物模型支架中以产生合适的组织形状。 马间充质干细胞

相关标签:马间充质干细胞 

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 推荐培养基:MSCM, Cat. No. 7501

储存:液氮

运输:干冰

用途:科研

Mesenchymal stem cells (MSC) are well-characterized population of adult stem cells. They have the potential to develop into mature cells that produce fat, cartilage, bone, tendons, and muscle [1, 2]. These properties in combination with their developmental plasticity have generated tremendous interest in the potential use of mesenchymal stem cells to replace damaged tissues. MSC cultured without serum in the presence of transformation growth factor will differentiate into chondrocytes, whereas MSC cultured in serum with ascorbic acid and dexamethasone will differentiate into osteoblasts. MSC has the capability for renewal and differentiation into various lineages of mesenchymal tissues. In essence MSC could be cultured to expand their numbers then transplanted to the injured site or after seeding in/on shaped biomimetic scaffold to generate appropriate tissue constructs.

HMSC-ad from ScienCell Research Laboratories are isolated from horse adipose tissue. HMSC-ad are cryopreserved at passage one culture and delivered frozen. Each vial contains >5 x 105 cells in 1 ml volume. HMSC-ad are characterized by immunofluorescent method with antibodies to CD44, CD90 and lipid staining after differentiation. HMSC-ad are negative for mycoplasma, bacteria, yeast and fungi. HMSC-ad are guaranteed to further culture at the conditions provided by ScienCell Research Laboratories.

Reference
1. Kassem, M. Mesenchymal stem cells: biological characteristics and potential clinical applications. 2004. Cloning Stem Cells. 6(4):369-74.
2. Barry, F. P., and J. M. Murphy. Mesenchymal stem cells: clinical applications and biological characterization. 2004. Int J Biochem Cell Biol. 36(4):568-84.

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