Human Cell^exp Human Recombinant TGF-beta 1

Product Name: Human Cell^exp Human Recombinant TGF-beta 1

Alternate Name/Synonyms: Transforming growth factor beta-1, TGF-beta-1, CED, DPD1, TGFB, TGF-b 1, LAP, TGFB1.

Gene Symbol: TGFB1

Accession #: P01137

Gene ID: 7040

Source: Human 293 cell expressed

Appearance: Lyophilized

Physical Form Description: Lyophilized from 50 mM sodium acetate, pH 4.5 ａnd 350 mM NaCl.

Molecular Weight: 25 kDa, homodimer, nonglycosylated

Purity by SDS-PAGE: ≥95%

Purity by HPLC: N/A

Endotoxin Level: < 1.0 EU per 1 μg of protein

Biological Activity: ED₅₀ is typically 0.1 to 0.5 ng/mL. The specific activity was determined by the dose-dependent inhibition of IL-4 induced proliferation of mouse HT-2 cells （BALB/c spleen activated by sheep erythrocytes in the presence of IL-2）.

Reconstitution Instructions: Reconstitute in sterile 4 mM HCl containing 0.1% endotoxin-free recombinant human serum albumin.

Storage Temp.: -80°C

Shipping: Gel pack

Background Information: Transforming growth factor betas （TGFβ） mediate many cell-cell interactions that occur during embryonic development. Three TGFβs have been identified in mammals. TGF Beta 1, TGF Beta 2 ａnd TGF Beta 3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. TGF-beta 1 is involved in hematopoiesis ａnd endothelial differentiation.

Amino Acid Sequence: N/A

Handling: Centrifuge the vial prior to opening

USAGE: For Research Use Only! Not For Use in Humans.