Human Cell^exp Human Recombinant TPO

Product Name: Human Cell^exp Human Recombinant TPO

Alternate Name/Synonyms: Megakaryocyte colony-stimulating factor, Myeloproliferative leukemia virus oncogene ligand, C-mpl ligand, ML, Megakaryocyte growth ａnd development factor, MGDF, TPO, MKCSF, MPLLG, MGC163194, THPO.

Gene Symbol: THPO

Accession #: P40225

Gene ID: 7066

Source: Human 293 cell expressed

Appearance: Lyophilized

Physical Form Description: Lyophilized in PBS.

Molecular Weight: 80 to 85 kDa, monomer, glycosylated

Purity by SDS-PAGE: > 95%

Purity by HPLC: N/A

Endotoxin Level: < 1.0 EU per 1 μg of protein

Biological Activity: ED₅₀ is typically 0.5 to 5 ng/mL. The specific activity was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells （human erythroleukemic indicator cell line）.

Reconstitution Instructions: Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.

Storage Temp.: -80°C

Shipping: Gel pack

Background Information: TPO （Thrombopoietin, also known as Mpl-ligand, MGDF）, a glycoprotein hormone produced mainly by the liver ａnd the kidney, stimulates the proliferation ａnd maturation of megakaryocytes ａnd promotes increased circulating levels of platelets in vivo. TPO signals through the c-mpl receptor ａnd acts as an important regulator of circulating platelets.

Amino Acid Sequence: N/A

Handling: Centrifuge the vial prior to opening

USAGE: For Research Use Only! Not For Use in Humans.