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UNC 1215

点击次数:312发布时间:2013/3/20 12:01:38

UNC 1215

更新日期:2022/8/19 17:45:40

所 在 地:美洲

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简单介绍:UNC 1215Product Name: UNC 1215 Alternate Name/Synonyms: (2-​(Phenylamino)-​1,​4-​phenylene)bis((4-​(pyrrolidin-​1-​yl)piperidin-​1-​yl)metha Description: Cell-permeable. A potent and selective chemical probe for the methyllysine (Kme)

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UNC 1215

Product Name: UNC 1215

Alternate Name/Synonyms: (2-​(Phenylamino)-​1,​4-​phenylene)bis((4-​(pyrrolidin-​1-​yl)piperidin-​1-​yl)metha

Description: Cell-permeable. A potent and selective chemical probe for the methyllysine (Kme) reading function of L3MBTL3, a member of the malignant brain tumor (MBT) family of chromatin-interacting transcriptional repressors. It binds L3MBTL3 with a Kd value of 120 nM (IC₅₀ = 40 nM), competitively displacing mono- or dimethyl-lysine containing peptides. UNC1215 is > 50-fold selective toward L3MBTL3 than other members of the human MBT family and demonstrates selectivity against more than 200 other Kme reader domains examined.

Peptide Sequence: N/A

Appearance: White to Off-white Solid

Formulation: N/A

CAS Number: 1415800-43-9

Molecular Formula: C32H43N5O2

Molecular Weight: 529.72

Purity: ≥98% by HPLC

Solubility: DMSO (50 mM)

Storage Temp.: -20°C

Shipping Conditions: gel pack Protect from light and moisture

Handling:

USAGE: For Research Use Only! Not For Use in Humans.

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