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UNC 1215
Product Name: UNC 1215
Alternate Name/Synonyms: (2-(Phenylamino)-1,4-phenylene)bis((4-(pyrrolidin-1-yl)piperidin-1-yl)metha
Description: Cell-permeable. A potent and selective chemical probe for the methyllysine (Kme) reading function of L3MBTL3, a member of the malignant brain tumor (MBT) family of chromatin-interacting transcriptional repressors. It binds L3MBTL3 with a Kd value of 120 nM (IC₅₀ = 40 nM), competitively displacing mono- or dimethyl-lysine containing peptides. UNC1215 is > 50-fold selective toward L3MBTL3 than other members of the human MBT family and demonstrates selectivity against more than 200 other Kme reader domains examined.
Peptide Sequence: N/A
Appearance: White to Off-white Solid
Formulation: N/A
CAS Number: 1415800-43-9
Molecular Formula: C32H43N5O2
Molecular Weight: 529.72
Purity: ≥98% by HPLC
Solubility: DMSO (50 mM)
Storage Temp.: -20°C
Shipping Conditions: gel pack Protect from light and moisture
Handling:
USAGE: For Research Use Only! Not For Use in Humans.