产品展示
Forskolin
点击次数：298发布时间：2013/3/25 10:10:41
更新日期：2022/8/19 17:45:40
所 在 地：美洲
产品型号：
优质供应
详细内容
Forskolin
技术数据:
分子量（MW）: 410.5 化学式: C22H34O7
溶解度: DMSO 82mg/mL Water <1mg/mL Ethanol 37mg/mL 纯度: >99% 稳定性: at -20℃ CAS号: 66575-29-9
生物活性
Forskolin increases cAMP levels in preparations of membranes, cells, or tissues. Forskolin not only activates AC but also interacts with certain other proteins, including glucose transporters ａnd ion channels. Forskolin is able to promote activation of nine different transmembrane iso-forms of AC, albeit with somewhat less efficacy for AC9, which could be used to provides a means to identify ａnd quantify high-affinity binding sites, i.e., G-proteins （Gs）–AC complexes. Activation of s by GPCRs contributes to Forskolin-stimulated cAMP generation in cells because of s-Forskolin potentiation of AC activity. Forskolin stimulates adenylate cyclase activity without interacting with cell surface receptors. Forskolin＇s potentiation of cAMP in turn inhibits basophil ａnd mast cell degranulation ａnd histamine release, lowers blood pressure ａnd intraocular pressure, inhibits platelet aggregation, promotes vasodilation, bronchodilation, ａnd thyroid hormone secretion, ａnd stimulates lipolysis in fat cells. Forskolin inhibits the binding of platelet-activating factor （PAF）, independently of cAMP formation, which may be a result of Forskolin＇s direct effect on PAF or via interference with PAF binding to receptor sites. Forskolin also appears to have an effect on several membrane transport proteins, ａnd inhibits glucose transport in erythrocytes, adipocytes, platelets, ａnd other cells. Forskolin is used to treat with glaucoma.
技术数据:
分子量（MW）: 410.5 化学式: C22H34O7
溶解度: DMSO 82mg/mL Water <1mg/mL Ethanol 37mg/mL 纯度: >99% 稳定性: at -20℃ CAS号: 66575-29-9
生物活性
Forskolin increases cAMP levels in preparations of membranes, cells, or tissues. Forskolin not only activates AC but also interacts with certain other proteins, including glucose transporters ａnd ion channels. Forskolin is able to promote activation of nine different transmembrane iso-forms of AC, albeit with somewhat less efficacy for AC9, which could be used to provides a means to identify ａnd quantify high-affinity binding sites, i.e., G-proteins （Gs）–AC complexes. Activation of s by GPCRs contributes to Forskolin-stimulated cAMP generation in cells because of s-Forskolin potentiation of AC activity. Forskolin stimulates adenylate cyclase activity without interacting with cell surface receptors. Forskolin＇s potentiation of cAMP in turn inhibits basophil ａnd mast cell degranulation ａnd histamine release, lowers blood pressure ａnd intraocular pressure, inhibits platelet aggregation, promotes vasodilation, bronchodilation, ａnd thyroid hormone secretion, ａnd stimulates lipolysis in fat cells. Forskolin inhibits the binding of platelet-activating factor （PAF）, independently of cAMP formation, which may be a result of Forskolin＇s direct effect on PAF or via interference with PAF binding to receptor sites. Forskolin also appears to have an effect on several membrane transport proteins, ａnd inhibits glucose transport in erythrocytes, adipocytes, platelets, ａnd other cells. Forskolin is used to treat with glaucoma.
技术数据:
分子量（MW）: 410.5 化学式: C22H34O7
溶解度: DMSO 82mg/mL Water <1mg/mL Ethanol 37mg/mL 纯度: >99% 稳定性: at -20℃ CAS号: 66575-29-9
生物活性
Forskolin increases cAMP levels in preparations of membranes, cells, or tissues. Forskolin not only activates AC but also interacts with certain other proteins, including glucose transporters ａnd ion channels. Forskolin is able to promote activation of nine different transmembrane iso-forms of AC, albeit with somewhat less efficacy for AC9, which could be used to provides a means to identify ａnd quantify high-affinity binding sites, i.e., G-proteins （Gs）–AC complexes. Activation of s by GPCRs contributes to Forskolin-stimulated cAMP generation in cells because of s-Forskolin potentiation of AC activity. Forskolin stimulates adenylate cyclase activity without interacting with cell surface receptors. Forskolin＇s potentiation of cAMP in turn inhibits basophil ａnd mast cell degranulation ａnd histamine release, lowers blood pressure ａnd intraocular pressure, inhibits platelet aggregation, promotes vasodilation, bronchodilation, ａnd thyroid hormone secretion, ａnd stimulates lipolysis in fat cells. Forskolin inhibits the binding of platelet-activating factor （PAF）, independently of cAMP formation, which may be a result of Forskolin＇s direct effect on PAF or via interference with PAF binding to receptor sites. Forskolin also appears to have an effect on several membrane transport proteins, ａnd inhibits glucose transport in erythrocytes, adipocytes, platelets, ａnd other cells. Forskolin is used to treat with glaucoma.
技术数据:
分子量（MW）: 410.5 化学式: C22H34O7
溶解度: DMSO 82mg/mL Water <1mg/mL Ethanol 37mg/mL 纯度: >99% 稳定性: at -20℃ CAS号: 66575-29-9
生物活性
Forskolin increases cAMP levels in preparations of membranes, cells, or tissues. Forskolin not only activates AC but also interacts with certain other proteins, including glucose transporters ａnd ion channels. Forskolin is able to promote activation of nine different transmembrane iso-forms of AC, albeit with somewhat less efficacy for AC9, which could be used to provides a means to identify ａnd quantify high-affinity binding sites, i.e., G-proteins （Gs）–AC complexes. Activation of s by GPCRs contributes to Forskolin-stimulated cAMP generation in cells because of s-Forskolin potentiation of AC activity. Forskolin stimulates adenylate cyclase activity without interacting with cell surface receptors. Forskolin＇s potentiation of cAMP in turn inhibits basophil ａnd mast cell degranulation ａnd histamine release, lowers blood pressure ａnd intraocular pressure, inhibits platelet aggregation, promotes vasodilation, bronchodilation, ａnd thyroid hormone secretion, ａnd stimulates lipolysis in fat cells. Forskolin inhibits the binding of platelet-activating factor （PAF）, independently of cAMP formation, which may be a result of Forskolin＇s direct effect on PAF or via interference with PAF binding to receptor sites. Forskolin also appears to have an effect on several membrane transport proteins, ａnd inhibits glucose transport in erythrocytes, adipocytes, platelets, ａnd other cells. Forskolin is used to treat with glaucoma.
技术数据:
分子量（MW）: 410.5 化学式: C22H34O7
溶解度: DMSO 82mg/mL Water <1mg/mL Ethanol 37mg/mL 纯度: >99% 稳定性: at -20℃ CAS号: 66575-29-9
生物活性
Forskolin increases cAMP levels in preparations of membranes, cells, or tissues. Forskolin not only activates AC but also interacts with certain other proteins, including glucose transporters ａnd ion channels. Forskolin is able to promote activation of nine different transmembrane iso-forms of AC, albeit with somewhat less efficacy for AC9, which could be used to provides a means to identify ａnd quantify high-affinity binding sites, i.e., G-proteins （Gs）–AC complexes. Activation of s by GPCRs contributes to Forskolin-stimulated cAMP generation in cells because of s-Forskolin potentiation of AC activity. Forskolin stimulates adenylate cyclase activity without interacting with cell surface receptors. Forskolin＇s potentiation of cAMP in turn inhibits basophil ａnd mast cell degranulation ａnd histamine release, lowers blood pressure ａnd intraocular pressure, inhibits platelet aggregation, promotes vasodilation, bronchodilation, ａnd thyroid hormone secretion, ａnd stimulates lipolysis in fat cells. Forskolin inhibits the binding of platelet-activating factor （PAF）, independently of cAMP formation, which may be a result of Forskolin＇s direct effect on PAF or via interference with PAF binding to receptor sites. Forskolin also appears to have an effect on several membrane transport proteins, ａnd inhibits glucose transport in erythrocytes, adipocytes, platelets, ａnd other cells. Forskolin is used to treat with glaucoma.
技术数据:
分子量（MW）: 410.5 化学式: C22H34O7
溶解度: DMSO 82mg/mL Water <1mg/mL Ethanol 37mg/mL 纯度: >99% 稳定性: at -20℃ CAS号: 66575-29-9
生物活性
Forskolin increases cAMP levels in preparations of membranes, cells, or tissues. Forskolin not only activates AC but also interacts with certain other proteins, including glucose transporters ａnd ion channels. Forskolin is able to promote activation of nine different transmembrane iso-forms of AC, albeit with somewhat less efficacy for AC9, which could be used to provides a means to identify ａnd quantify high-affinity binding sites, i.e., G-proteins （Gs）–AC complexes. Activation of s by GPCRs contributes to Forskolin-stimulated cAMP generation in cells because of s-Forskolin potentiation of AC activity. Forskolin stimulates adenylate cyclase activity without interacting with cell surface receptors. Forskolin＇s potentiation of cAMP in turn inhibits basophil ａnd mast cell degranulation ａnd histamine release, lowers blood pressure ａnd intraocular pressure, inhibits platelet aggregation, promotes vasodilation, bronchodilation, ａnd thyroid hormone secretion, ａnd stimulates lipolysis in fat cells. Forskolin inhibits the binding of platelet-activating factor （PAF）, independently of cAMP formation, which may be a result of Forskolin＇s direct effect on PAF or via interference with PAF binding to receptor sites. Forskolin also appears to have an effect on several membrane transport proteins, ａnd inhibits glucose transport in erythrocytes, adipocytes, platelets, ａnd other cells. Forskolin is used to treat with glaucoma.
技术数据:
分子量（MW）: 410.5 化学式: C22H34O7
溶解度: DMSO 82mg/mL Water <1mg/mL Ethanol 37mg/mL 纯度: >99% 稳定性: at -20℃ CAS号: 66575-29-9
生物活性
Forskolin increases cAMP levels in preparations of membranes, cells, or tissues. Forskolin not only activates AC but also interacts with certain other proteins, including glucose transporters ａnd ion channels. Forskolin is able to promote activation of nine different transmembrane iso-forms of AC, albeit with somewhat less efficacy for AC9, which could be used to provides a means to identify ａnd quantify high-affinity binding sites, i.e., G-proteins （Gs）–AC complexes. Activation of s by GPCRs contributes to Forskolin-stimulated cAMP generation in cells because of s-Forskolin potentiation of AC activity. Forskolin stimulates adenylate cyclase activity without interacting with cell surface receptors. Forskolin＇s potentiation of cAMP in turn inhibits basophil ａnd mast cell degranulation ａnd histamine release, lowers blood pressure ａnd intraocular pressure, inhibits platelet aggregation, promotes vasodilation, bronchodilation, ａnd thyroid hormone secretion, ａnd stimulates lipolysis in fat cells. Forskolin inhibits the binding of platelet-activating factor （PAF）, independently of cAMP formation, which may be a result of Forskolin＇s direct effect on PAF or via interference with PAF binding to receptor sites. Forskolin also appears to have an effect on several membrane transport proteins, ａnd inhibits glucose transport in erythrocytes, adipocytes, platelets, ａnd other cells. Forskolin is used to treat with glaucoma.
技术数据:
分子量（MW）: 410.5 化学式: C22H34O7
溶解度: DMSO 82mg/mL Water <1mg/mL Ethanol 37mg/mL 纯度: >99% 稳定性: at -20℃ CAS号: 66575-29-9
生物活性
Forskolin increases cAMP levels in preparations of membranes, cells, or tissues. Forskolin not only activates AC but also interacts with certain other proteins, including glucose transporters ａnd ion channels. Forskolin is able to promote activation of nine different transmembrane iso-forms of AC, albeit with somewhat less efficacy for AC9, which could be used to provides a means to identify ａnd quantify high-affinity binding sites, i.e., G-proteins （Gs）–AC complexes. Activation of s by GPCRs contributes to Forskolin-stimulated cAMP generation in cells because of s-Forskolin potentiation of AC activity. Forskolin stimulates adenylate cyclase activity without interacting with cell surface receptors. Forskolin＇s potentiation of cAMP in turn inhibits basophil ａnd mast cell degranulation ａnd histamine release, lowers blood pressure ａnd intraocular pressure, inhibits platelet aggregation, promotes vasodilation, bronchodilation, ａnd thyroid hormone secretion, ａnd stimulates lipolysis in fat cells. Forskolin inhibits the binding of platelet-activating factor （PAF）, independently of cAMP formation, which may be a result of Forskolin＇s direct effect on PAF or via interference with PAF binding to receptor sites. Forskolin also appears to have an effect on several membrane transport proteins, ａnd inhibits glucose transport in erythrocytes, adipocytes, platelets, ａnd other cells. Forskolin is used to treat with glaucoma.
技术数据:
| 分子量（MW）: | 410.5 | |
|---|---|---|
| 化学式: | C22H34O7 | |
| 溶解度: | DMSO 82mg/mL Water <1mg/mL Ethanol 37mg/mL | |
| 纯度: | >99% | |
| 稳定性: | at -20℃ | |
| CAS号: | 66575-29-9 |
生物活性
Forskolin increases cAMP levels in preparations of membranes, cells, or tissues. Forskolin not only activates AC but also interacts with certain other proteins, including glucose transporters ａnd ion channels. Forskolin is able to promote activation of nine different transmembrane iso-forms of AC, albeit with somewhat less efficacy for AC9, which could be used to provides a means to identify ａnd quantify high-affinity binding sites, i.e., G-proteins （Gs）–AC complexes. Activation of s by GPCRs contributes to Forskolin-stimulated cAMP generation in cells because of s-Forskolin potentiation of AC activity. Forskolin stimulates adenylate cyclase activity without interacting with cell surface receptors. Forskolin＇s potentiation of cAMP in turn inhibits basophil ａnd mast cell degranulation ａnd histamine release, lowers blood pressure ａnd intraocular pressure, inhibits platelet aggregation, promotes vasodilation, bronchodilation, ａnd thyroid hormone secretion, ａnd stimulates lipolysis in fat cells. Forskolin inhibits the binding of platelet-activating factor （PAF）, independently of cAMP formation, which may be a result of Forskolin＇s direct effect on PAF or via interference with PAF binding to receptor sites. Forskolin also appears to have an effect on several membrane transport proteins, ａnd inhibits glucose transport in erythrocytes, adipocytes, platelets, ａnd other cells. Forskolin is used to treat with glaucoma.
