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人生发基质细胞

点击次数:182发布时间:2013/4/24 14:56:46

人生发基质细胞

更新日期:2022/8/19 17:45:54

所 在 地:美洲

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简单介绍:人生发基质细胞人生发基质细胞位于毛球基部的乳头周围,属于再生细胞范畴。它是毛发生长和毛发中黑色素转运的主要来源。在毛发生长的活跃阶段,基质中的细胞快速增长和分化导致毛发增长。生发基质细胞经历被称为角质化的过程,形成一层角蛋白以抑制毛发脱落。毛囊具有基质细胞的免疫特权。滤泡细胞培植研究表明生发基质细胞能通过植入毛乳头细胞来诱导新毛囊形成。 人生发基质细胞(HHGMC) 提取于人毛囊的生发基质,原代冻存。每管含有细胞数>5×105 cells/ml,此细胞通过Fibronectin and CD105免疫荧光染色验证,经测试不含有HIV-1、HBV、HCV、支原体、细菌、酵母和真

相关标签:人生发基质细胞 HHGMC 

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人生发基质细胞             
                     
            
上海义森生物科技有限公司

人生发基质细胞位于毛球基部的乳头周围,属于再生细胞范畴。它是毛发生长和毛发中黑色素转运的主要来源。在毛发生长的活跃阶段,基质中的细胞快速增长和分化导致毛发增长。生发基质细胞经历被称为角质化的过程,形成一层角蛋白以抑制毛发脱落。毛囊具有基质细胞的免疫特权。滤泡细胞培植研究表明生发基质细胞能通过植入毛乳头细胞来诱导新毛囊形成。    人生发基质细胞HHGMC提取于人毛囊的生发基质,原代冻存。每管含有细胞数>5×105 cells/ml,此细胞通过Fibronectin and CD105免疫荧光染色验证,经测试不含有HIV-1HBVHCV、支原体、细菌、酵母和真菌。细胞可以达到15倍增。

推荐培养基:(MSCM, Cat. No. 7501)

产地:San Diego,US储存:液氮

品牌:ScienCell

运输:干冰

用途:科研

The Germinal matrix is an area of reproducing cells situated around the papilla at the base of the hair bulb. It is the source of hair growth and transfer melanin to hair to give it pigmentation. During the active hair growth phase, cells in the matrix rapidly grow and differentiate, causing the hair to elongate. Cells of the germinal matrix under go a process called keratinization, which is the formation of a layer of the protein keratin, keeping the hair from falling out. Hair follicle has a complex immunologic profile, with immunologically "privileged" matrix cells [1]. Follicular cell implantation studies indicate that germinal matrix cells may induce new hair follicle formation by implanted dermal papilla cells [2].

HHGMC from ScienCell Research Laboratories are isolated from germinal matrix of hair follicle bulb. HHGMC are cryopreserved at passage one culture and delivered frozen. Each vial contains >5 x 105 cells in 1 ml volume. HHGMC are characterized by their mesenchymal cell morphology and immunofluorescent method with antibody to fibronectin and CD105. HHGMC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HHGMC are guaranteed to further expand for 15 population doublings at the condition provided by ScienCell Research Laboratories.

Reference
[1] Pus, R., Cotsarelis, G. (2005) The biology of hair follicles. Mechanisms of Disease 341:491-497.
[2] Cooley, J. (2004) Follicular cell implantation: an update on "hair follicle cloning". Facial Plast Surg Clin N Am 12:219-224.

Fig. 1. Phase contrast morphology of cultured HHGMC (passage two), 200X. Fig. 2. Relief contrast morphology of cultured HHGMC (passage two), 400X.


 

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