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人肾上腺微血管内皮细胞
点击次数：230发布时间：2013/4/25 15:12:50
更新日期：2022/8/19 17:45:54
所 在 地：美洲
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详细内容
人肾上腺微血管内皮细胞
上海义森生物科技有限公司
Description
The adrenal gland plays an essential role in regulating homeostasis in the body through the secretion of corticosteroid ａnd androgen hormones. The secreted steroids arise from three zones that form the adrenal gland: the zona glomerulosa, zona fasciculate, ａnd zona reticularis. Microvascular endothelial cells line the blood vessels ａnd contribute to many biological processes such as hemostasis, coagulation, trafficking of lymphocytes, ａnd the inflammatory response. Microvascular endothelial cells （MEC） are of importance in the adrenal gland for their regulatory function on the secretion of adrenal hormones [1]. Studies have shown that factors secreted from HAdMEC, such as endothelin-1, nitric oxide, adrenomedullin ａnd PAMP affect aldosterone secretion [2]. HAdMEC differ from MECs from different organs in function ａnd phenotype [3]. For example, compared to brain MEC ａnd liver MEC, adrenal MEC are highly resistant to glucocorticoid-induced cytotoxicity showing that MECs are specialized to the tissues they belong to [4].
HAdMEC from ScienCell Research Laboratories are isolated from human adrenal tissue. HAdMEC are cryopreserved at passage one ａnd delivered frozen. Each vial contains >5 x 10 5 cells in 1 ml volume. HAdMEC are characterized by immunofluorescent method with antibodies to vWF/Factor VIII ａnd CED31 （P-CAM）. HAdMEC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast ａnd fungi. HAdMEC are guaranteed to further culture for 15 population doublings in the conditions provided by ScienCell Research Laboratories
Recommended Medium
It is recommended to use Endothelial Cell Medium （ECM, cat. no. 1001） for the culturing of HAdMEC in vitro.
Product Use
HAdMEC are for research use only. It is not approved for human or animal use, or for application in in vitro diagnostic procedures.
Storage
Directly ａnd immediately transfer cells from dry ice to liquid nitrogen upon receiving ａnd keep the cells in liquid nitrogen until cell culture needed for experiments.
Shipping
Dry ice.
Reference
[1][2] Hinson, J.P., Kapas, S. 1998. The role of endothelial cell product in the regulation of adrenocortical functions: actions of endothelin, nitric oxide, adrenomedullin ａnd PAMP. Horm Metab Res. 30（6-7）: 334-40
[3] Gu, F., Zhang, WJ., Wu, LQ., Ye, LY., Li, HZ., Li, J., Xu, SQ., XU, YP., Lou, JN. 2006. Characteristics of human adrenal microvascular endothelial cells in morphology, phenotypes, ａnd function. Ahonqquo Yi Xue Ke Xue Yuan Xue Bao. 28（4）:502-6
Description
The adrenal gland plays an essential role in regulating homeostasis in the body through the secretion of corticosteroid ａnd androgen hormones. The secreted steroids arise from three zones that form the adrenal gland: the zona glomerulosa, zona fasciculate, ａnd zona reticularis. Microvascular endothelial cells line the blood vessels ａnd contribute to many biological processes such as hemostasis, coagulation, trafficking of lymphocytes, ａnd the inflammatory response. Microvascular endothelial cells （MEC） are of importance in the adrenal gland for their regulatory function on the secretion of adrenal hormones [1]. Studies have shown that factors secreted from HAdMEC, such as endothelin-1, nitric oxide, adrenomedullin ａnd PAMP affect aldosterone secretion [2]. HAdMEC differ from MECs from different organs in function ａnd phenotype [3]. For example, compared to brain MEC ａnd liver MEC, adrenal MEC are highly resistant to glucocorticoid-induced cytotoxicity showing that MECs are specialized to the tissues they belong to [4].
HAdMEC from ScienCell Research Laboratories are isolated from human adrenal tissue. HAdMEC are cryopreserved at passage one ａnd delivered frozen. Each vial contains >5 x 10 5 cells in 1 ml volume. HAdMEC are characterized by immunofluorescent method with antibodies to vWF/Factor VIII ａnd CED31 （P-CAM）. HAdMEC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast ａnd fungi. HAdMEC are guaranteed to further culture for 15 population doublings in the conditions provided by ScienCell Research Laboratories
Recommended Medium
It is recommended to use Endothelial Cell Medium （ECM, cat. no. 1001） for the culturing of HAdMEC in vitro.
Product Use
HAdMEC are for research use only. It is not approved for human or animal use, or for application in in vitro diagnostic procedures.
Storage
Directly ａnd immediately transfer cells from dry ice to liquid nitrogen upon receiving ａnd keep the cells in liquid nitrogen until cell culture needed for experiments.
Shipping
Dry ice.
Reference
[1][2] Hinson, J.P., Kapas, S. 1998. The role of endothelial cell product in the regulation of adrenocortical functions: actions of endothelin, nitric oxide, adrenomedullin ａnd PAMP. Horm Metab Res. 30（6-7）: 334-40
[3] Gu, F., Zhang, WJ., Wu, LQ., Ye, LY., Li, HZ., Li, J., Xu, SQ., XU, YP., Lou, JN. 2006. Characteristics of human adrenal microvascular endothelial cells in morphology, phenotypes, ａnd function. Ahonqquo Yi Xue Ke Xue Yuan Xue Bao. 28（4）:502-6
Description
The adrenal gland plays an essential role in regulating homeostasis in the body through the secretion of corticosteroid ａnd androgen hormones. The secreted steroids arise from three zones that form the adrenal gland: the zona glomerulosa, zona fasciculate, ａnd zona reticularis. Microvascular endothelial cells line the blood vessels ａnd contribute to many biological processes such as hemostasis, coagulation, trafficking of lymphocytes, ａnd the inflammatory response. Microvascular endothelial cells （MEC） are of importance in the adrenal gland for their regulatory function on the secretion of adrenal hormones [1]. Studies have shown that factors secreted from HAdMEC, such as endothelin-1, nitric oxide, adrenomedullin ａnd PAMP affect aldosterone secretion [2]. HAdMEC differ from MECs from different organs in function ａnd phenotype [3]. For example, compared to brain MEC ａnd liver MEC, adrenal MEC are highly resistant to glucocorticoid-induced cytotoxicity showing that MECs are specialized to the tissues they belong to [4].
HAdMEC from ScienCell Research Laboratories are isolated from human adrenal tissue. HAdMEC are cryopreserved at passage one ａnd delivered frozen. Each vial contains >5 x 10 5 cells in 1 ml volume. HAdMEC are characterized by immunofluorescent method with antibodies to vWF/Factor VIII ａnd CED31 （P-CAM）. HAdMEC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast ａnd fungi. HAdMEC are guaranteed to further culture for 15 population doublings in the conditions provided by ScienCell Research Laboratories
Recommended Medium
It is recommended to use Endothelial Cell Medium （ECM, cat. no. 1001） for the culturing of HAdMEC in vitro.
Product Use
HAdMEC are for research use only. It is not approved for human or animal use, or for application in in vitro diagnostic procedures.
Storage
Directly ａnd immediately transfer cells from dry ice to liquid nitrogen upon receiving ａnd keep the cells in liquid nitrogen until cell culture needed for experiments.
Shipping
Dry ice.
Reference
[1][2] Hinson, J.P., Kapas, S. 1998. The role of endothelial cell product in the regulation of adrenocortical functions: actions of endothelin, nitric oxide, adrenomedullin ａnd PAMP. Horm Metab Res. 30（6-7）: 334-40
[3] Gu, F., Zhang, WJ., Wu, LQ., Ye, LY., Li, HZ., Li, J., Xu, SQ., XU, YP., Lou, JN. 2006. Characteristics of human adrenal microvascular endothelial cells in morphology, phenotypes, ａnd function. Ahonqquo Yi Xue Ke Xue Yuan Xue Bao. 28（4）:502-6
