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Mouse Microglia
上海义森生物科技有限公司
Description
Microglia, one of the glial cell types in the CNS, are an important integral component of neuro-glial cell network [1]. They have been observed in the brain parenchyma from the early stage of development to the mature state. Microglia act as brain macrophages when programmed cell death occurs during brain development or when the CNS is injured or pathologically damaged. Microglia can be considered as the main cell in brain immune surveillance, can present antigens in the molecular context of MHC class II expression to CD-4 positive T cells, are capable of Fc-mediated phagocytosis, ａnd share many common antigens with hemopoietic ａnd tissue macrophages [2]. Furthermore, there is accumulating evidence that microglia are involved in a variety of physiological ａnd pathological processes in the brain by interacting with neurons ａnd other glial cells ａnd through production of biologically active substances such as growth factors, cytokines, ａnd other factors [3].
MM from ScienCell Research Laboratories are isolated from primary mouse brain cell culture. Cryopreserved MM are frozen after purification without further expansion ａnd delivered frozen. Each vial contains >1 x 106 cells in 1 ml volume. MM culture in different size of vessels is about 90% confluent ａnd delivered in gel ice. MM is characterized by immunofluorescent method with antibody to OX-42 （CD 11b/c）. MM is negative mycoplasma, bacteria, yeast ａnd fungi. MM is guaranteed to further culture in the condition provided by ScienCell Research Laboratories.
Recommended Medium
It is recommended to use microglia medium （MM, Cat. No. 1901） for the culturing of mouse microglia in vitro.Product Use
MM are for research use only. They are not approved for human or animal use, or for application in in vitro diagnostic procedures.Storage
Transfer cells directly ａnd immediately from dry ice to liquid nitrogen upon receiving ａnd keep the cells in liquid nitrogen until cell culture is needed for experiments.
Description
Microglia, one of the glial cell types in the CNS, are an important integral component of neuro-glial cell network [1]. They have been observed in the brain parenchyma from the early stage of development to the mature state. Microglia act as brain macrophages when programmed cell death occurs during brain development or when the CNS is injured or pathologically damaged. Microglia can be considered as the main cell in brain immune surveillance, can present antigens in the molecular context of MHC class II expression to CD-4 positive T cells, are capable of Fc-mediated phagocytosis, ａnd share many common antigens with hemopoietic ａnd tissue macrophages [2]. Furthermore, there is accumulating evidence that microglia are involved in a variety of physiological ａnd pathological processes in the brain by interacting with neurons ａnd other glial cells ａnd through production of biologically active substances such as growth factors, cytokines, ａnd other factors [3].
MM from ScienCell Research Laboratories are isolated from primary mouse brain cell culture. Cryopreserved MM are frozen after purification without further expansion ａnd delivered frozen. Each vial contains >1 x 106 cells in 1 ml volume. MM culture in different size of vessels is about 90% confluent ａnd delivered in gel ice. MM is characterized by immunofluorescent method with antibody to OX-42 （CD 11b/c）. MM is negative mycoplasma, bacteria, yeast ａnd fungi. MM is guaranteed to further culture in the condition provided by ScienCell Research Laboratories.
Recommended Medium
It is recommended to use microglia medium （MM, Cat. No. 1901） for the culturing of mouse microglia in vitro.Product Use
MM are for research use only. They are not approved for human or animal use, or for application in in vitro diagnostic procedures.Storage
Transfer cells directly ａnd immediately from dry ice to liquid nitrogen upon receiving ａnd keep the cells in liquid nitrogen until cell culture is needed for experiments.
Description
Microglia, one of the glial cell types in the CNS, are an important integral component of neuro-glial cell network [1]. They have been observed in the brain parenchyma from the early stage of development to the mature state. Microglia act as brain macrophages when programmed cell death occurs during brain development or when the CNS is injured or pathologically damaged. Microglia can be considered as the main cell in brain immune surveillance, can present antigens in the molecular context of MHC class II expression to CD-4 positive T cells, are capable of Fc-mediated phagocytosis, ａnd share many common antigens with hemopoietic ａnd tissue macrophages [2]. Furthermore, there is accumulating evidence that microglia are involved in a variety of physiological ａnd pathological processes in the brain by interacting with neurons ａnd other glial cells ａnd through production of biologically active substances such as growth factors, cytokines, ａnd other factors [3].MM from ScienCell Research Laboratories are isolated from primary mouse brain cell culture. Cryopreserved MM are frozen after purification without further expansion ａnd delivered frozen. Each vial contains >1 x 106 cells in 1 ml volume. MM culture in different size of vessels is about 90% confluent ａnd delivered in gel ice. MM is characterized by immunofluorescent method with antibody to OX-42 （CD 11b/c）. MM is negative mycoplasma, bacteria, yeast ａnd fungi. MM is guaranteed to further culture in the condition provided by ScienCell Research Laboratories.
