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小鼠肾小管上皮细胞

点击次数:253发布时间:2013/4/26 14:17:13

小鼠肾小管上皮细胞

更新日期:2022/8/19 17:45:54

所 在 地:美洲

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简单介绍:小鼠肾小管上皮细胞DescriptionRenal tubular epithelial cells (RTEpiC) play a crucial role in renal function. They reabsorb nearly all of the glucose and amino acids in the glomerular filtrate, while allowing other substances of no nutritional value to be excreted in the urine. They are also a major site o

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小鼠肾小管上皮细胞             
                     
            
上海义森生物科技有限公司

Description

Renal tubular epithelial cells (RTEpiC) play a crucial role in renal function. They reabsorb nearly all of the glucose and amino acids in the glomerular filtrate, while allowing other substances of no nutritional value to be excreted in the urine. They are also a major site of injury in a variety of congenital, metabolic, and inflammatory diseases. RTEpiC can produce inflammatory mediators such as cytokines and chemokines and actively participate in acute inflammatory processes by affecting and directing leukocyte chemotaxis via the production of IL-8 [1, 2]. RTEpiC express IL-2R alpha and MHC class II antigens during inflammation after renal transplantation or in crescentic glomerulonephritis indicating the capacity to participate in the pathogenesis of immune renal injury [3]. To be able to study the relationship between tubular cells and a variety of renal diseases, the MTEpiC culture provides a useful in vitro model.

MRTEpiC from ScienCell Research Laboratories are isolated from neonate mouse kidney. MRTEpiC are cryopreserved at passage one and delivered frozen. Each vial contains >5 x 105 cells in 1 ml volume. MRTEpiC are characterized by immunofluorescent method with antibodies to cytokeratin-18, -19 and vimentin. MRTEpiC are negative for mycoplasma, bacteria, yeast and fungi. MRTEpiC are guaranteed to further expand for 5 population doublings in the condition provided by ScienCell Research Laboratories.

Recommended Medium

It is recommended to use Epithelial Cell Medium-animal (EpiCM-a, Cat. No. 4131) for expanding MRTEpiC in vitro.

Product Use

MRTEpiC are for research use only. It is not approved for human or animal use, or for application in in vitro diagnostic procedures.

Storage

Directly and immediately transfer cells from dry ice to liquid nitrogen upon receiving and keep the cells in liquid nitrogen until cell culture is needed for experiments.


 

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