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小鼠心肌细胞

点击次数:234发布时间:2013/4/26 14:25:53

小鼠心肌细胞

更新日期:2022/8/19 17:45:54

所 在 地:美洲

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简单介绍:小鼠心肌细胞DescriptionThe cardiac myocyte is the most physically energetic cell in the body. Its contraction is myogenic, i.e. it is independent of nervous stimulation. All cardiac myocyte are capable of spontaneous rhythmic depolarization and repolarization of their membrane. Cardiac myocytes occupy

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小鼠心肌细胞            
                     
            
上海义森生物科技有限公司

Description

The cardiac myocyte is the most physically energetic cell in the body. Its contraction is myogenic, i.e. it is independent of nervous stimulation. All cardiac myocyte are capable of spontaneous rhythmic depolarization and repolarization of their membrane. Cardiac myocytes occupy as much as 75% of cardiac mass but constitute only about one third of the total cell number in the heart. They are highly specialized high-oxygen-content cells and house a large number of mitochondria [1]. Differentiated cardiac myocytes have little capacity to proliferate and show the hypertrophic growth in response to alpha1-adrenergic stimuli via the Ras/MEK pathway [2]. Cardiac myocyte hypertrophy and apoptosis have been implicated in the loss of contractile function during heart failure. Cardiac myocytes have a complex network of signals that regulates their essential role in the rhythmic pumping of the heart [3]. This network is an appealing model system in which to study the basic principles of cellular signaling mechanisms leading to cardiac myocyte death.

MCM from ScienCell Research Laboratories are isolated from neonate mouse heart (ventricle). MCM are cryopreserved on primary cultures and delivered frozen. Each vial contains >1 x 106 cells in 1 ml volume. MCM are characterized by immunofluorescent method with antibodies to myosin. MCM are negative mycoplasma, bacteria, yeast and fungi. MCM are guaranteed to further culture at the conditions provided by ScienCell Research Laboratories.

Recommended Medium

It is recommended to use Cardiac Myocyte Medium (CMM, Cat. No. 6201) for the culturing of MCM in vitro.

Product Use

MCM are for research use only. It is not approved for human or animal use, or for application in in vitro diagnostic procedures.

Storage

Directly and immediately transfer cells from dry ice to liquid nitrogen upon receiving and keep the cells in liquid nitrogen until cell culture needed for experiments.


 

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