产品展示
Recombinant Murine IL-1a厂家直销
点击次数：28发布时间：2016/1/26 13:26:46
更新日期：2016/1/26 13:26:46
所 在 地：中国大陆
产品型号：211-11A
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详细内容
产品编号:
211-11A
别名:
Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)
描述:
IL-1α is a non-secreted, proinflammatory cytokine produced in a variety of cells, including monocytes, tissue macrophages, keratinocytes ａnd other epithelial cells. Both IL-1α ａnd IL-1β bind to the same receptor ａnd have similar, if not identical, biological properties. These cytokines have a broad range of activities including the stimulation of thymocyte proliferation by inducing IL-2 release, B-cell maturation ａnd proliferation, mitogenic FGF-like activity, ａnd the release of prostaglandin ａnd collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant Murine IL-1α is a 17.9 kDa protein containing 156 amino acid residues.
氨基酸序列:
SAPYTYQSDL RYKLMKLVRQ KFVMNDSLNQ TIYQDVDKHY LSTTWLNDLQ QEVKFDMYAY SSGGDDSKYP VTLKISDSQL FVSAQGEDQP VLLKELPETP KLITGSETDL IFFWKSINSK NYFTSAAYPE LFIATKEQSR VHLARGLPSM TDFQIS
来源:
E.coli
纯度:
Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.
生物活性:
The ED50 as determined by the dose-dependent stimulation of murine D10S cells is < 0.002 ng/ml, corresponding to a specific activity of > 5 x 108units/mg.
交叉反应:
Mouse, Human, Rat + Chicken
研究领域:
原产国:
USA
仅用于研究。不适用于诊断或治疗。
