产品展示
Recombinant Human IL-13新品现货
点击次数：41发布时间：2016/1/26 14:16:18
更新日期：2016/1/26 14:16:18
所 在 地：中国大陆
产品型号：200-13
优质供应
详细内容
产品编号:
200-13
别名:
NC30 (Human), P600 (Murine)
描述:
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, ａnd also by mast cells ａnd NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development ａnd indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes ａnd macrophages ａnd it inhibits the expression of inflammatory cytokines such as IL-1β, TNF-α, IL-6 ａnd IL-8. IL-13 has also been shown to enhance B cell proliferation ａnd to induce isotype switching, resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human ａnd murine IL-13 are cross-species reactive. Recombinant Human IL-13 is a 12.6 kDa protein consisting of 115 amino acid residues.
氨基酸序列:
MSPGPVPPST ALRELIEELV NITQNQKAPL CNGSMVWSIN LTAGMYCAAL ESLINVSGCS AIEKTQRMLS GFCPHKVSAG QFSSLHVRDT KIEVAQFVKD LLLHLKKLFR EGRFN
来源:
E.coli
纯度:
Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.
生物活性:
The ED50 as determined by the dose-dependent proliferation of TF-1 cells was ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106units/mg.
交叉反应:
Mouse, Human, Bacteria, Leech, Monkey, Pig
研究领域:
原产国:
USA
仅用于研究。不适用于诊断或治疗。
