产品展示
Recombinant Murine IL-17 Peprotech厂家
点击次数：41发布时间：2016/1/26 14:24:02
更新日期：2016/1/26 14:24:02
所 在 地：中国大陆
产品型号：210-17
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详细内容
产品编号:
210-17
别名:
IL-17, CTLA-8
描述:
The originally described IL-17 protein, now known as IL-17A, is a homodimer of two 136 amino acid chains that are secreted by activated T-cells, which act on stromal cells to induce production of proinflammatory ａnd hematopoietic bioactive molecules. Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region, but differ from one another in their N-terminal regions ａnd in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17A exhibits cross-species bioactivity between human ａnd murine cells. Recombinant Murine IL-17A is a 30.0 kDa, disulfide-linked homodimer of two 133 amino acid, polypeptide chains.
氨基酸序列:
AAIIPQSSAC PNTEAKDFLQ NVKVNLKVFN SLGAKVSSRR PSDYLNRSTS PWTLHRNEDP DRYPSVIWEA QCRHQRCVNA EGKLDHHMNS VLIQQEILVL KREPESCPFT FRVEKMLVGV GCTCVASIVR QAA
来源:
E.coli
纯度:
Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.
生物活性:
Measured by its ability to induce IL-6 production by NIH 3T3 cells.
交叉反应:
Rat, Mouse, Human
研究领域:
原产国:
USA
仅用于研究。不适用于诊断或治疗。
