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现货供应北京210-12 Recombinant Murine IL-12价格

点击次数：336发布时间：2013/9/10 14:55:16

更新日期：2022/12/30 11:21:23

所在地：中国大陆

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简单介绍：北京现货 210-12 Recombinant Murine IL-12 Peprotech 2ug 价格北京雅安达生物技术有限公司：提供外包服务单克隆抗体纯化：A或G蛋白亲和，免费测抗体亚类、多克隆抗体纯化，量大优惠，欢迎来电咨询！

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Recombinant Murine IL-12

北京雅安达生物技术有限公司提供外包服务：抗体HRP标记、抗原HRP标记、抗体胶体金标记、0.01%胶体金标记50-100ml、抗体FITC标记价格优惠！欢迎来电咨询！010-57269780 北京现货 210-12 Recombinant Murine IL-12 Peprotech 2ug 价格

Catalog Number:

210-12

Synonyms:

NKSF, CTL maturation factor （TCMF）, Cytotoxic lymphocyte maturation factor （CLMF）, TSF

Description:

IL-12 is a potent regulator of cell mediated immune responses ａnd it induces IFN-γ production by NK ａnd T cells. It is produced by activated monocytes/macrophage cells, B lymphocytes ａnd connective tissue type mast cells. Among its biological activities IL-12 promotes the growth ａnd activity of activated NK, CD4+ ａnd CD8+ cells ａnd induces the development of IFN-γ producing Th1 cells. Recombinant murine IL-12 is a 75.0 kDa heterodimeric glycoprotein consisting of disulfide-linked 35 kDa （p35）ａnd 40 kDa （p40） subunits （506 total amino acid residues）.

AA Sequence:

p35 Subunit:RVIPVSG PARCLSQSRN LLKTTDDMVK TAREKLKHYS CTAEDIDHED ITRDQTSTLK TCLPLELHKN ESCLATRETS STTRGSCLPP QKTSLMMTLC LGSIYEDLKM YQTEFQAINA ALQNHNHQQI ILDKGMLVAI DELMQSLNHN GETLRQKPPV GEADPYRVKM KLCILLHAFS TRVVTINRVM GYLSSA

p40 Subunit:MWELEKD VYVVEVDWTP DAPGETVNLT CDTPEEDDIT WTSDQRHGVI GSGKTLTITV KEFLDAGQYT CHKGGETLSH SHLLLHKKEN GIWSTEILKN FKNKTFLKCE APNYSGRFTC SWLVQRNMDL KFNIKSSSSS PDSRAVTCGM ASLSAEKVTL DQRDYEKYSV SCQEDVTCPT AEETLPIELA LEARQQNKYE NYSTSFFIRD IIKPDPPKNL QMKPLKNSQV EVSWEYPDSW STPHSYFSLK FFVRIQRKKE KMKETEEGCN QKGAFLVEKT STEVQCKGGN VCVQAQDRYY NSSCSKWACV PCRVRS

Source:

CHO cells

Purity:

Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.

Biological Activity:

Assay #1: The ED₅₀ was determined by the stimulation of IFN-gamma production by murine splenocytes co-stimulated with IL-18 is < 0.1 ng/ml, corresponding to a specific activity of > 1 x 10⁷ units/mg.
Assay #2: Determined by its ability to stimulate the proliferation of 2D6 cells. The expected ED₅₀ is ≤0.1ng/ml, corresponding to a specific activity of ≥1 x 10⁷ units/mg.

Cross Reactivity:

Human, Mouse, N/A, Cow + Mouse

Research Interests: