产品展示
优质供应
详细内容
Peprotech 220-11 Recombinant Murine IL-11
品名：Recombinant Murine IL-11 /重组小鼠白介素11
规格：2UG/10UG
品牌：Peprotech
货号：220-11
Peprotech 220-11 Recombinant Murine IL-11
Catalog Number:
220-11
Synonyms:
AGIF （Adipogenesis inhibitory factor）
Description:
IL-11 is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells ａnd osteoclasts. It is expressed in a wide variety of tissues including thymus, lung, bone, connective tissue ａnd central nervous system. IL-11 plays an important regulatory role in hematopoiesis by stimulating growth of myeloid, erythroid ａnd megakaryocyte progenitor cells. It also regulates bone metabolism, inhibits production of proinflammatory cytokines ａnd protects against gastromucosal injury. Recombinant Murine IL-11 is a 19.1 kDa protein consisting of 179 amino acid residues.
AA Sequence:
MPGPPAGSPR VSSDPRADLD SAVLLTRSLL ADTRQLAAQM RDKFPADGDH SLDSLPTLAM SAGTLGSLQL PGVLTRLRVD LMSYLRHVQW LRRAGGPSLK TLEPELGALQ ARLERLLRRL QLLMSRLALP QAAPDQPVIP LGPPASAWGS IRAAHAILGG LHLTLDWAVR GLLLLKTRL
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.
Biological Activity:
The ED50 was determined by the dose-dependent stimulation of the proliferation of murine T11 cells is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg.
Peprotech 220-11 Recombinant Murine IL-11
Cross Reactivity:
Mouse
