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Recombinant Murine IL-2
Catalog Number:
212-12
Synonyms:
T-cell growth factor （TCGF）, Aldesleukin
Description:
IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation ａnd other fundamental functions which are essential for the immune response. IL-2 stimulates growth ａnd differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages ａnd oligodendrocytes. Recombinant murine IL-2 is a 17.2 kDa protein, containing 149 amino acid residues.
AA Sequence:
PTSSSTSSST AEAQQQQQQQ QQQQQHLEQL LMDLQELLSR MENYRNLKLP RMLTFKFYLP KQATELKDLQ CLEDELGPLR HVLDLTQSKS FQLEDAENFI SNIRVTVVKL KGSDNTFECQ FDDESATVVD FLRRWIAFCQ SIISTSPQ
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.
Biological Activity:
The ED50 as determined by the dose dependent stimulation of murine CTLL-2 cells is < 0.2 ng/ml, corresponding to a specific activity of > 5 x 106 units/mg.
Cross Reactivity:
Human, Mouse, Leech, N/A
Research Interests:
 | AIDS / HIV |  | Cancer |
 | Cell Culture |  | Diabetes / Weight Regulation |
 | Immune System |  | Inflammation |
 | Neurobiology |  | Proliferation |
 | Stem Cells & Differentiation |  | Wound Healing |
 | Allergy |  | Transplantation |
Country of Origin:
USA
