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PeproTech原装 重组人嗜酸性粒细胞趋化因子(CCL24)
点击次数:342发布时间:2014/9/16 14:40:15
更新日期:2022/12/30 11:22:42
所 在 地:中国大陆
产品型号:
优质供应
详细内容
PeproTech原装 重组人嗜酸性粒细胞趋化因子(CCL24)
Recombinant Human Eotaxin-2 (CCL24)
Catalog Number:
300-33
Synonyms:
CCL24, MPIF-2, CkB-6
Description:
Eotaxin-2 is a CC chemokine that signals through the CCR3 receptor. It is produced by activated monocytes and T lymphocytes. Eotaxin-2 selectively chemoattracts cells expressing CCR3, including eosinophils, basophils, Th2 T cells, mast cells, and certain subsets of dendritic cells. Additionally, Eotaxin-2 inhibits the proliferation of multipotential hematopoietic progenitor cells. The mature protein, which also includes a C-terminal truncation, contains 78 amino acid residues (92 a.a. residues for the murine homolog, without C-terminal truncation). Eotaxin-2 contains the four conserved cysteine residues present in CC chemokines. Recombinant Human Eotaxin-2 is an 8.8 kDa protein containing 78 amino acid residues.
AA Sequence:
VVIPSPCCMF FVSKRIPENR VVSYQLSSRS TCLKGGVIFT TKKGQQFCGD PKQEWVQRYM KNLDAKQKKA SPRARAVA
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
Determined by its ability to chemoattract using human peripheral blood eosinophils using a concentration of 50.0-100.0 ng/ml.
Cross Reactivity:
Mouse, Human, Bacteria
Research Interests:
Chemotaxis | Immune System | ||
Wound Healing |
Country of Origin:
USA
Research Use Only. Not for use in diagnostic or therapeutic procedures.