产品展示
Peprotech原装450-34 β-NGF因子5ug/20ug报价
点击次数：864发布时间：2015/4/9 14:03:52
更新日期：2022/12/30 11:23:07
所 在 地：中国大陆
产品型号：
优质供应
详细内容
450-34
别名:
NGF-β, beta-Nerve Growth Factor
描述:
β-NGF is a neurotrophic factor structurally related to BDNF, NT-3 ａnd NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. β-NGF is a potent neurotrophic factor that signals through its receptor β-NGFR, ａnd plays a crucial role in the development ａnd preservation of the sensory ａnd sympathetic nervous systems. β-NGF also acts as a growth ａnd differentiation factor for B lymphocytes, ａnd enhances B-cell survival. The functional form of Recombinant Murine β-NGF is a non-covalently-linked homodimer of two 13.4 kDa, polypeptide monomers that each contain 120 amino acids ａnd three disulfide bonds, which are required for biological activity.
氨基酸序列:
SSTHPVFHMG EFSVCDSVSV WVGDKTTATD IKGKEVTVLA EVNINNSVFR QYFFETKCRA SNPVESGCRG IDSKHWNSYC TTTHTFVKAL TTDEKQAAWR FIRIDTACVC VLSRKATRRG
来源:
E.coli
纯度:
Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.
生物活性:
The ED50 as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106 units/mg.
交叉反应:
Human, Mouse
原产国:
原产国:
USA
仅用于研究。不适用于诊断或治疗。
