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技术文章

磷脂PEG衍生物DSPE-PEG-AC,磷脂-聚乙二醇-炔基

点击次数:22 发布时间:2023/10/25 15:48:09
 英文名称:DSPE-PEG-AC,DSPE-PEG-Acrylate

English name:AC-PEG-DSPE,Acrylate-PEG-DSPE

中文名称:磷脂-聚乙二醇-炔基

Chinese name:磷脂-PEG-炔基

Acrylate-PEG-DSPE,一种磷脂PEG衍生物,用于脂质体制备,磷脂化聚乙二醇结合具有亲水性和疏水性,聚乙二醇磷脂脂质体形成材料,能够用于medicinal输送、基因转染和疫苗传递。聚乙二醇化磷脂可以明显的改善blood circulation时间和稳定封装medicinal。丙烯酸酯功能化PEG是制备生物相容性和生物可降解水凝胶及其它生物聚合物的常用聚合物。

Acrylate-PEG-DSPE, a phospholipid PEG derivative, is used for lipid preparation. Phosphatidylated polyethylene glycol binding has hydrophilicity and hydrophobicity. Polyethylene glycol phospholipid liposomes form high-quality materials that can be used for medical delivery, gene transfection, and vaccine delivery. Polyethylene glycol phospholipids can significantly improve the blood circulation time and stabilize the packaging of medical. Acrylate functionalized PEG is a common polymer for preparing biocompatible and biodegradable hydrogels and other biopolymers。

1,2-二硬脂酰基-sn-甘油-3-磷酸乙酰胺-聚乙二醇是一种PEG修饰的脂质。它是一种长循环的脂质体膜,在水分散体中形成胶束,表面活性剂的临界胶束浓度(CMC)比低102倍,因此medicinal稳定性更好,即使通过blood稀释,也能保持胶束颗粒的完整性,具有一定的靶向性,丙烯酸酯可以自聚合,也可以与其他单体共聚。它是一种用于制造粘合剂、合成树脂、特种橡胶和塑料的单体。

1,2-distearoyl-sn-glycerol-3-phosphoacetamide-polyethylene glycol is a PEG modified lipid. It is a long circulating liposome membrane that forms micelles in aqueous dispersions. The critical micelle concentration (CMC) of surfactants is 102 times lower, making it more stable. Even if diluted by blood, it can maintain the integrity of micelle particles and has a certain degree of targeting. Acrylates can self polymerize and copolymerize with other monomers. It is a monomer used in the manufacture of adhesives, synthetic resins, special rubbers, and plastics.

功能化的聚乙二醇可以用来修饰蛋白质,肽和材料,也可以增加溶解度和稳定性,降低多肽和蛋白质免疫原性。它还可以抑制带电分子非特异性结合体去修饰表面。该产品可应用于医学研究,medicinal释放,纳米技术和新材料研究,细胞培养。以及配体研究,多肽合成支持,接枝高分子化合物,新材料和聚乙二醇改性功能涂层等活性化合物方面。

Functionalized polyethylene glycol can be used to modify proteins, peptides, and materials, as well as increase solubility and stability, reducing the immunogenicity of polypeptides and proteins. It can also inhibit the non specific binding of charged molecules to modify the surface. This product can be used in medical research, medical release, nanotechnology and new material research, and cell culture. And ligand research, peptide synthesis support, grafting polymer compounds, new materials, and polyethylene glycol modified functional coatings and other active compounds.

MV:可定制,磷脂-PEG 1-炔基、DSPE-PEG 2-AC,磷脂-聚乙二醇 3.4-炔基、DSPE-PEG 10-Acrylate、DSPE-聚乙二醇 20-Acrylate、磷脂-peg 5-炔基

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原创作者:西安凯新生物科技有限公司

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