小动物儿茶酚胺遥测系统
价格：￥电议
品牌名称：$brandModel.Title(进口品牌)型号： 原产地：美洲 发布时间：2021/1/7 15:58:51更新时间：2024/11/24 20:09:47
产品摘要：小动物儿茶酚胺遥测系统采用快速扫描循环伏安法(FSCV)的工作原理，门用于儿茶酚胺(i.e., dopamine, norepinephrine, and serotonin)的测量。可以用于测量自由清醒活动状态下的动物。该遥测系统适用于大鼠。
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详细内容
BIOSENSORS生物酶传感器用于在大小鼠清醒自由的状态下监测其脑内的化学物质的变化，它反应迅速、特异性高、实时精确。实验人员可以将生物酶传感器与数据采集器和软件相配合，用于数据的记录和分析。生物传感器将是在体检测神经递质浓度的有力工具。
可以检测的参数：
谷氨酸
葡萄糖
乳酸
脑组织氧浓度
生物酶传感器以酶为介质检测分析物的浓度，当分析物与特异性的酶发生化学反应生成过氧化氢后，再通过铂铱电发生氧化反应而产生电流 ，大脑中存在的电活性干扰物质通过被动式选择性膜被排除，必要时可主动清除。
主要特点：
反应迅速: 快速生理活动时中的分析物检测
高特异性：排除脑内存在的内源性电活性干扰物
线性反应: 对不同浓度的标准也产生线性的氧化电流
主要应用方向：
在体监测动物脑内微环境中化学物质的浓度变化
在行为学和生理活动时检测动物脑内的神经递质变化
药物筛选 ，包括神经药理作用
生物标记物监测
l Voltage Span: -1.1 V to +1.3 V
l Range: 250 – 400 V/s
l Sweeps/second: 5 - 10
l Points/sweep: 1000
Dopamine (blue), serotonin (green), ａnd norepinephrine (pink) have specific voltammogram profiles when detected by FSCV.
The TETHERED FAST SCAN CYCLIC VOLTAMMETRY (FSCV) SYSTEM allows researchers to harness the powerful genetics of the mouse model to address underlying mechanisms of biogenic neurotransmitter release ａnd function. A headmounted FSCV board sends signals through a low-torque commutator to an interface box that streams data to the host PC. The system comes with Pinnacle’s FREE 8500 software.
1. The FSCV interface box provides access to stimulus lines ａnd transmits data to PAL-8500 software.
2. A low-torque commutator, which is mounted above the cage, allows for unencumbered freedom of movement.
3. Signals are amplified ａnd filtered at the head of the animal using our headstage, which ensures the delivery of clean, artifact-free data.
4. Stereotaxically placed guide cannulas allow easy insertion of carbon fiber sensors. Headmounts are affixed to the skull with dental acrylic ａnd act as a connection port for the headstage.
CARBON FIBER
Pinnacle’s FSCV system uses CARBON FIBER SENSORS (CFSs) to measure the presence of dopamine ａnd other catecholamines in the brains of freely moving animals. Our sensor is a 34 µm diameter carbon fiber housed in a silica sheath that extends 0.5 mm beyond the end of the silica. All Pinnacle CFSs require an Ag/AgCl reference electrode.
Our sensor is a 34 um diameter carbon fiber housed in a silica sheath that extends 0.5 mm beyond the end of the silica.
FSCV PAL-8500 SOFTWARE PACKAGE
The FSCV system includes Pinnacle’s FREE PAL-8500 software, which supports traditional, short recording paradigms (recordings of two minutes or less) as well as longer-term recordings that use an extended continuous mode. Furthermore, the suite supports integrated, synchronized video recording, which allows monitoring of animal behavior simultaneously with biogenic amine release.
Additional features of this software include:
• Background Subtraction
• 3D Visualization
• User-Selectable Filters
• Heat Maps
• Animated Voltammograms
• Export to Third-Party Packages
您想了解更多详细资料吗？
请与我们联系：
TEL ： 021-35183767 ， 18502129044
QQ ： 3007536033
Mail： yuyan0317@126.com
敬请来电咨询！
可以检测的参数：
谷氨酸
葡萄糖
乳酸
脑组织氧浓度
生物酶传感器以酶为介质检测分析物的浓度，当分析物与特异性的酶发生化学反应生成过氧化氢后，再通过铂铱电发生氧化反应而产生电流 ，大脑中存在的电活性干扰物质通过被动式选择性膜被排除，必要时可主动清除。
主要特点：
反应迅速: 快速生理活动时中的分析物检测
高特异性：排除脑内存在的内源性电活性干扰物
线性反应: 对不同浓度的标准也产生线性的氧化电流
主要应用方向：
在体监测动物脑内微环境中化学物质的浓度变化
在行为学和生理活动时检测动物脑内的神经递质变化
药物筛选 ，包括神经药理作用
生物标记物监测
FAST SCAN CYCLIC VOLTAMMETRY SYSTEM
Pinnacle’s FAST SCAN CYCLIC VOLTAMMETRY (FSCV) SYSTEM is specifically designed to simplify the measurement of catecholamines (i.e., dopamine, norepinephrine, ａnd serotonin). Pinnacle offers turn-key systems for both mice ａnd rats. Both the wireless rat system and the tethered mouse system use carbon fiber sensors to enable short-term measurement in the brains of freely moving animals.HOW IT WORKSBiogenic amine levels are detected by rapidly cycling a voltage across an implanted carbon fiber sensor ａnd measuring the resultant current. Our systems can measure spontaneous sub-second neurotransmitter release events while conducting detailed behavioral studies. Both the wireless ａnd tethered systems sweep from 250 to 400 V/s in a user-selectable range spanning -1.1 to +1.3 V. All systems have built-in support for controlling an external stimulus.l Voltage Span: -1.1 V to +1.3 V
l Range: 250 – 400 V/s
l Sweeps/second: 5 - 10
l Points/sweep: 1000
Analysis
Dopamine (blue), serotonin (green), ａnd norepinephrine (pink) have specific voltammogram profiles when detected by FSCV.
The TETHERED FAST SCAN CYCLIC VOLTAMMETRY (FSCV) SYSTEM allows researchers to harness the powerful genetics of the mouse model to address underlying mechanisms of biogenic neurotransmitter release ａnd function. A headmounted FSCV board sends signals through a low-torque commutator to an interface box that streams data to the host PC. The system comes with Pinnacle’s FREE 8500 software.
1. The FSCV interface box provides access to stimulus lines ａnd transmits data to PAL-8500 software.
2. A low-torque commutator, which is mounted above the cage, allows for unencumbered freedom of movement.
3. Signals are amplified ａnd filtered at the head of the animal using our headstage, which ensures the delivery of clean, artifact-free data.
4. Stereotaxically placed guide cannulas allow easy insertion of carbon fiber sensors. Headmounts are affixed to the skull with dental acrylic ａnd act as a connection port for the headstage.
CARBON FIBER
Pinnacle’s FSCV system uses CARBON FIBER SENSORS (CFSs) to measure the presence of dopamine ａnd other catecholamines in the brains of freely moving animals. Our sensor is a 34 µm diameter carbon fiber housed in a silica sheath that extends 0.5 mm beyond the end of the silica. All Pinnacle CFSs require an Ag/AgCl reference electrode.
Our sensor is a 34 um diameter carbon fiber housed in a silica sheath that extends 0.5 mm beyond the end of the silica.
CARBON FIBER SENSORS
Carbon fiber sensors are ordered by cannula type ａnd whether the researcher needs to remove them from the cannula for post-calibration. CFS-F sensors are fixed in the cannula ａnd cannot be removed for post-calibration。FSCV PAL-8500 SOFTWARE PACKAGE
The FSCV system includes Pinnacle’s FREE PAL-8500 software, which supports traditional, short recording paradigms (recordings of two minutes or less) as well as longer-term recordings that use an extended continuous mode. Furthermore, the suite supports integrated, synchronized video recording, which allows monitoring of animal behavior simultaneously with biogenic amine release.
Additional features of this software include:
• Background Subtraction
• 3D Visualization
• User-Selectable Filters
• Heat Maps
• Animated Voltammograms
• Export to Third-Party Packages
您想了解更多详细资料吗？
请与我们联系：
TEL ： 021-35183767 ， 18502129044
QQ ： 3007536033
Mail： yuyan0317@126.com
敬请来电咨询！
