中文名称：

Toll样受体4抗体

英文名称：

  TLR4 Antibody

其他名称：

  Toll-like receptor 4; hToll; CD284; TLR4

产品品牌：

   Abbiotec

产品编号：

251110

产品规格：

  0.1mg

产品包装：

  一支包装（原装进口）

免 疫 原：

   KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human TLR4.

背景介绍：

Toll-like receptor family (TLR) has a fundamental role in pathogen recognition ａnd activation of innate immunity. TLRs are highly conserved from Drosophila to humans ａnd share structural ａnd functional similarities. TLRs recognize pathogen-associated molecular patterns (PAMP) that are expressed on infectious agents, ａnd mediate the production of cytokines necessary for the development of effective immunity. Toll-like receptor 4 (TLR4) cooperates with LY96 ａnd CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88, TIRAP ａnd TRAF6 to lead to NFkB activation, cytokine secretion ａnd inflammatory response. TLR4 is highly expressed in placenta, spleen ａnd peripheral blood leukocytes. Genetic variation in TLR4 is associated with age-related macular degeneration 10 (ARMD10), an irreversible vision loss.

应用范围：

 E，WB，IHC

产品资料：

www.abbiotec.com （美国Abbiotec公司 ）

更多产品

  www.otwobiotech.com （华拓生物中文网）

品牌  ​

产品编号

产品名称

英文名称

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