中文名称：

  巨噬细胞克隆刺激因子抗体

英文名称：

  Anti-M-CSF (Macrophage Colony Stimulating Factors)

其他名称：

  Macrophage Colony Stimulating Factors; Colony stimulating factor 1 (macrophage); Colony stimulating factor 1; Colony stimulating factor macrophage specific; CSF 1; CSF1; Csfm; Lanimostim; M CSF; Macrophage Colony Stimulating Factor 1; MCSF; MGC31930. 

产品品牌：

  pllabs

产品编号：

  PL031042R

产品规格：

  0.2mg

产品包装：

  一支包装（原装进口、进口分装）

免 疫 原：

   KLH conjugated synthetic peptide derived from mouse MCSF C-terminus

克隆类型：

   Rabbit Polyclonal IgG

背景介绍：

   Four distinct colony-stimulating factors (CSFs) that promote survival, proliferation ａnd differentiation of bone marrow precursor cells have been well characterized: granulocyte macrophage CSF (GMCSF), granulocyte CSF (GCSF), macrophage CSF (MCSF), ａnd Interleukin-3 (IL-3, Multi CSF). Both GMCSF ａnd IL-3 are multipotential growth factors, stimulating proliferation of progenitor cells from more than one hematopoietic lineage. In contrast, GCSF ａnd MCSF are lineage restricted hematopoietic growth factors, stimulating final mitotic divisions ａnd the terminal cellular maturation of the partially differentiated hematopoietic progenitors. Macrophage CSF, also known as CSF1, is produced by monocytes, fibroblasts ａnd endothelial cells. It stimulates the formation of macrophage colonies, enhances antibody-dependent, cell-mediated cytotoxicity by monocytes ａnd macrophages, ａnd inhibits bone resorption by osetoclasts. Natural human MCSF is a dimeric glycoprotein of 70-90 kD molecular weight, existing in multiple glycosylation forms. It binds to a 165 kD glycoprotein of the receptor tyrosine kinase subclass III, a family that includes the receptors for platelet derived growth factor (PDGF) ａnd stem cell factor (SCF). 

应用范围：

   Human, Mouse, Rat, （Please decide the specificity by homology）

产品资料：

   www.pllabs.com  （加拿大Pllabs公司）

更多产品：

   www.otwobiotech.com （华拓生物中文网）